Therapeutic Discovery for Neurodevelopmental Disorders, Postdoctoral Fellowship
This is a unique opportunity for a postdoctoral fellowship to boost your career and participate in translational research to save children's lives, conveniently located in the warm Miami metropolitan area.
A postdoctoral position is available immediately at the Scripps Research Institute on Jupiter, Florida campus to participate in developing treatments for a devastating neurodevelopmental disorder caused by mutations in the GNAO1 gene with the aim to go into clinical trials within 12 months.
You will be privileged with an opportunity to be a part of the pioneering multinational effort, involving researchers from different countries and institutions working together to develop a novel gene therapy to save and improve the lives of many unfortunate children. The position is supported by the fellowship from the Child’s Cure Genetic Research and CureGNAO1 Foundations.
The project offers a unique opportunity to leverage the state-of-the-art translational capabilities of the Institute to develop innovative pharmaco-genetic strategies for disease correction while participating in basic research on neuronal signaling mechanisms. The laboratory takes a multidisciplinary approach combining genetic mouse models, proteomics, electrophysiology, imaging, and innovative optical sensor technologies to study neuronal signaling and develop corrective strategies for neuropsychiatric disorders.
We are looking for a highly-motivated and self-driven individual who wishes to work creatively in an independent setting. Successful candidates will have an extensive research experience as evidenced by a strong publication record.
Experience in one or more of the following areas is highly desirable:
(1) molecular genetic approaches to study cellular signaling (2) neuronal cell cultures and iPS technology, (3) Animal models of disease (4) viral transduction approaches (5) optical reporter assays (6) experience with AAVs, antisense oligonucleotides and RNAi is a plus
We encourage applications from highly experienced candidates and compensation will commensurate with experience level.
To apply, please send CV, brief description of research interests and contact information of references to Dr. Kirill Martemyanov at firstname.lastname@example.org. The Scripps Research Institute provides an outstanding intellectual environment and access to a wide range of cutting edge technologies and the PI is committed to the career development of trainees.
Internal Number: GNAO1-2020-60
About Scripps Research Neuroscience
The main emphasis of the research in the laboratory is on the fundamental principles that regulate signaling via G protein coupled receptors (GPCR). GPCRs mediate a vast variety of critical biological processes ranging from proliferation and motility to cellular reception and excitability. GPCR signaling pathways are of particular importance for the nervous system function where they control many fundamental processes including excitability, differentiation, sensory perception and synaptic transmission. Importantly, but not surprisingly, even subtle imbalances in GPCR signaling often lead to the most profound nervous system disorders ranging from blindness and cognitive problems to grave neurological diseases.