The Prion Disease Laboratory at UC San Diego is seeking an enthusiastic postdoctoral researcher to join our multidisciplinary team dedicated to unravelling the mechanisms of neurotoxicity in prion and Alzheimer's disease. We use iPSCs, primary neurons, molecular and biochemistry techniques, and transgenic mouse models. We are investigating the molecular basis for neurotoxicity, the endo-lysosomal pathway, autophagy, synaptic damage, as well as how protein aggregates spread from cell-to-cell within the brain.
Projects include understanding the mechanisms of prion spread between cells and through the glymphatic pathway, selective neuronal vulnerability in prion disease, mechanisms underlying neurotoxicity. Our team is highly interactive with other teams across UCSD and on the La Jolla Mesa, as well as internationally.
Additional information can be found at http://sigurdsonlab.ucsd.edu.
The University of California, San Diego is located on the La Jolla Mesa in close proximity to The Scripps Research Institute, the Salk Institute, and the Sanford Burnham Prebys Medical Discovery Institute Research and provides a highly stimulating, collaborative, and interactive research environment in a beautiful location.
Please send curriculum vitae and contact information for three references to: Christina Sigurdson , D.V.M., Ph.D., Dept. of Pathology, UCSD, 9500 Gilman Drive, La Jolla, CA 92093-0612; e-mail: firstname.lastname@example.org.
Successful candidates will be highly motivated and have research experience in neuroscience, cell biology, biochemistry and/or molecular biology, and mouse genetics and excellent communication skills.
Internal Number: 3931
About UC San Diego
The neurodegenerative disease research community at UC San Diego is vibrant and highly collaborative.