Postdoctoral positions are available in Williams’ lab in the Department of Ophthalmology and Visual Sciences at Washington University School of Medicine. The main focus of this research project is on determining mechanisms of neural degeneration and regeneration in order to develop therapeutic strategies for trauma and degenerative conditions.
The Williams lab is a newly established research group at the Washington University School of Medicine. The candidate will be working closely with Dr. Philip R. Williams. We use the visual system, primarily the mouse retina and optic nerve, to study native mechanisms of neuronal persistence and regrowth in the face of injury and degenerative diseases. Our techniques span in vivo two photon microscopy, transcriptomics, mouse models of neurodegenerative diseases and gene therapy. We also collaborate with labs that have expertise in electrophysiology, ex vivo calcium imaging and large scale 3-dimensional electron microscopy. At the mechanistic level, our lab is interested in multiple pathways that influence cell survival and regeneration including: alterations to circuit activity, growth factor signaling, influence of primary signaling on the growth state, metabolic and energetic mechanisms of coping with stress. The ultimate goals of these projects are both to discover biomarkers for at risk cell and patient populations, and to develop new approaches towards therapeutic development.
For more information about the lab please visit https://sites.wustl.edu/williams/home/
The environment at the Washington University School of Medicine is highly collaborative. Candidates will have access to multiple state of the art core facilities to support their research projects. In addition to high-quality research facilities, career and professional development training for postdoctoral researchers is provided through the Office of Postdoctoral Affairs, Career Center, Teaching Center, and campus groups. Candidates will also have opportunities to teach by mentoring talented graduate and undergraduate students.
Postdoctoral fellows at Washington University receive a starting salary based on the NIH NRSA guidelines and a generous benefit package. Complete information on the benefit package is located on the WUSM Human Resources Benefits Website: http://medschoolhr.wustl.edu. Additional information on being a postdoc at Washington University in St. Louis can be found at postdoc.wustl.edu/prospective-postdocs.
A successful candidate will be enthusiastic and possess a strong interest in neural degeneration and regeneration. Applicants should be recent PhD (or equivalent) graduates in Neuroscience or related fields with experience in transcriptomic material generation and analysis, in vivo 2-photon microscopy, adeno-associated virus production and use, experimental design, and data analysis.
Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.