Neuroscience laboratory at the University of California, San Francisco (UCSF) seeks a qualified, experienced and dynamic Postdoctoral Fellow. The successful candidate will advance our program to use zebrafish in epilepsy research. Our laboratory developed and characterized the first acute (Baraban et al. Neuroscience 2005; Hunt et al. Exp. Neurol. 2012) and genetic (Hortopan et al. J. Neurosci. 2010; Baraban et al. Nat. Comm. 2013; Grone et al. PloS One 2016) models of epilepsy in zebrafish. We are currently using these models in high-throughput drug screening, neurodevelopmental studies, and calcium imaging projects. We are also using CRISPR/Cas9 gene editing technology to generate zebrafish mutant lines for all known human epilepsy genes. Both projects are supported by grants from the National Institutes of Health (NIH).
Using larval zebrafish, we plan to establish new pipelines for the analysis and monitoring of seizures, as well as discover and develop novel therapies for genetic forms of epilepsy. Studies using larval zebrafish incorporate a variety of approaches already established in the lab: electrophysiology recording in vivo, locomotion tracking, pharmacology, CRISPR/Cas9 editing, qPCR, microfluidics, computational (MATLAB) analysis, light sheet microscopy, and fast confocal imaging of brain networks in fluorescent reporter fish.
We are currently seeking a highly motivated individual to participate in these projects.
UCSF offers an outstanding neuroscience community and desirable San Francisco location.
If you are interested in a postdoc position in our lab, send an email to firstname.lastname@example.org that includes your CV and contact information for at least two references. Please also send a brief 1-page description of your research interests describing your past research experience, future goals, and how you envision your contribution to the overall research direction of the Baraban Lab.
Competitive applicants will have:
at least one first-author publication in a high-quality journal
a sincere interest in epilepsy research
Internal Number: 2019001
UCSF is part of the 10-campus University of California, the world’s premier public research university system, and the only of its campuses dedicated to graduate and professional education. Driven by our public mission, we are a collection of dedicated scientists, clinicians, students and staff who strive to make the world a better place through our singular focus on health. Compassion is as critical as discovery in fulfilling our mission to make a difference for individual patients and whole populations.