The Department of Orthopedic Surgery seeks a Postdoctoral Research Scientist to study paired brain and spinal cord electrical stimulation to promote recovery of movement following central nervous system injury. The project employs electrophysiology to test hypotheses about how to strengthen sensorimotor integration in the spinal cord. We are also developing and testing a closed loop system for applying spinal cord stimulation based on levels of brain activity from movement intent. The successful applicant will be motivated to understand the systems-level mechanisms of a powerful neuromodulation paradigm developed recently in the laboratory. In addition, the project involves viral manipulation of neural circuits, anatomical tracing imaged with tissue clearing, and novel assays of skilled forelimb function. These and many other skills and cutting-edge techniques will be taught to the successful candidate. The scientist will join a dynamic and growing group of 9 investigators in the Movement Recovery Laboratory led by Jason Carmel, MD, PhD at Columbia University Irving Medical Center. All projects use activity-based therapies, especially electrical stimulation, to promote neurological recovery after injury. Compensation includes NIH scale salary and Columbia University benefits. A commitment of at least 2 years of full-time work is required; the term may be renewable. Management responsibilities may be included for a strong candidate.
A PhD (or equivalent) in Neuroscience, Biomedical Engineering, or other field related directly to the research; Experience with Neurophysiology techniques Strong analytical and reasoning skills Strong writing skills and a track record of publications
Experience in motor or somatosensory systems Spinal cord and muscle recording and stimulation Closed loop systems Matlab or similar programming and analysis Familiarity with brain and spinal cord injury Experience with activity- or injury-induced neural plasticity
Internal Number: 0000345
About Columbia Orthopedics
The Department of Orthopedic Surgery at Columbia University College of Physicians and Surgeons is committed to providing world-class training to the next generation of orthopedic surgeons — and the opportunity for you to become involved in groundbreaking research.
The Orthopedics Research Group is a recognized leader in many areas of orthopedic research. In affiliation with the Columbia University College of Physicians & Surgeons, the International Center for Health Outcomes & Innovation Research (InCHOIR), and the Columbia-Presbyterian Medical Center, our vision is to improve musculoskeletal health through excellent clinical evaluative research and to gain national and international prominence in this endeavor.
The mission of the Orthopedic Research Group is (a) to perform quality clinical research. (b) to improve the quality of clinical care by developing new analytical methods for evaluating medical treatments and applying these methods to innovate approaches to patient care, (c) to promote advancement of health outcomes in research, (d) to educate all levels of health care provides in health sciences research. (d) to investigate and disseminate the health policy implication...s of our research findings and to use these data to empower pediatric health policy advocates. In particular, our group maintains the following research objectives:
To design new innovative research projects that promote innovation, public policy, and clinical exposure;
To streamline the process of clinical research by modifying and standardizing routine data collection that will incorporate quality of life (QOL) questionnaire into clinical practice and enable every parent and/or child to complete the questionnaire;
To strengthen and expand high quality, interdisciplinary, clinical evaluative and policy research at the Health Sciences Campus of Columbia University;
To develop a clinical research curriculum;
To investigate and disseminate the health policy implications of our research findings and to use these data to empower health policy advocates.