The fellow will conduct research investigating the pathological changes in subcortical sleep-wake nuclei that occur in Alzheimer’s disease and other tauopathies. The fellow will obtain advanced training in neuroanatomy, neurohistology and quantitative human neuropathology in order to facilitate experiments geared toward understanding the biological basis of sleep disturbances presented clinically in patients with AD and related disorders. The environment will further provide opportunities to pursue correlations between brain pathology and antemortem clinical or imaging findings.
PhD in neuroscience or related fields and a career interest in neurodegenerative disease. Preference will be given to applicants with prior training in mammalian anatomy and quantitative stereology and a capacity to blend neuroanatomy with molecular biological approaches, but all interested applicants are encouraged to apply.
Applications will be reviewed on an ongoing basis until the position is filled. Please direct inquiries to Dr. Grinberg by sending a letter of interest, CV and at least three references to firstname.lastname@example.org.
Internal Number: 123
About University of California, San Francisco
Dr. Grinberg is a neuropathologist specializing in brain aging and associated disorders. She received her medical and doctorate degrees in São Paulo, Brazil. In 2003, Dr. Grinberg, along with colleagues from several disciplines founded a brain bank in São Paulo, Brazil, which has developed into an extremely prolific and highly regarded institution. Her doctorate work was focused in the neuropathology of frontotemporal lobar degeneration. From 2007 to 2009, Dr. Grinberg acquired expertise in neuroanatomy and in the use of state-of-the-art methods for tridimensional brain reconstruction at the University of Würzburg, Germany. This knowledge is being utilized in several projects, including a R01 funded study in which the overarching goal is to provide an integrated picture of brainstem vulnerability in AD and FTLD-TDP and to incorporate this understanding into their etiopathogenesis, testing the hypothesis that selected brainstem nuclei are interdependently and consistently involved in very early stages of AD and FTLD-TDP. Currently, Dr. Grinberg is an Associate Professor at the UCSF Memory and Aging Center. In 2009, she was the recipient of the UNESCO-L'Oréal Award "For Women in Scie...nce" and in 2010 of the John Douglas French Alzheimer Foundation "Distinguished Research Scholar Award." She is also the chairwoman of the HUPO Brain Proteome Project since 2013.