In the Neurodegenerative Diseases Laboratory led by Robert Baloh, MD, PhD, the goal is to understand mechanisms of neurodegenerative diseases including amyotrophic lateral sclerosis and peripheral neuropathy using human disease genes as our guide, in an effort to develop effective treatments for these disorders.
The Baloh Lab is currently seeking a Postdoctoral Scientist to study the molecular mechanisms of neurodegeneration with focus on mitochondrial function and dynamics and their role in axonal and cellular integrity. This is an excellent opportunity to work with a multidisciplinary group of neurologists, molecular biologists and neurogeneticists interested in understanding neurodegeneration with the goal of developing therapies. The primary focus of the Postdoctoral Scientist will be studying molecular mechanisms of neurodegeneration resulting from altered mitochondrial dynamics, which impacts a range of diseases including inherited neuropathy, motor neuron disease/ALS, Parkinson’s and Alzheimer’s disease.
The ideal candidate will have experience with:
A broad range of techniques including molecular biology and genetic engineering, mitochondrial analysis and live cell imaging, tissue culture including iPSC differentiation, transcriptomic analysis, and disease modeling in rodents
Performing routine and complex laboratory procedures throughout the training period
Developing, adapting, and implementing new research techniques and protocols, and analyzing and interpreting data
Participating in publications and presentations as author or co-author
Additional Expectations and Job Duties:
May assist in preparation of grant proposals, but is not responsible for generating grant funds
Designs and performs experiments, keeping appropriate experimental records and documentation and analyze the results with the Principal Investigator
Operates and maintains equipment and instruments
Participation in laboratory meetings, keeping a lab notebook, performing calculations, tabulating data, summarizing methods and results of related experiments and general lab maintenance
Function efficiently and cooperatively with a team of faculty, research associates, technicians and students
Scheduling flexibility to include evening, weekend and holiday rotation commitment is required
Excellent written and oral communication skills
Travel may be required
Doctorate (MD, PhD, VMD or DDS) in an area directly related to the field of research specialization
Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis and operation and maintenance of specialized equipment
Knowledge of safety standards and maintenance of specialized equipment
Lifting, standing, walking
Internal Number: 18002072
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