The newly formed Soldner laboratory at the Albert Einstein College of Medicine in New York City is seeking highly motivated, successful, and creative individual(s) with a background in neuroscience, stem cell biology, and molecular genetics.
The main focus of the Soldner laboratory is modeling human brain development and function in vitro as a tool to systematically investigate the genetic, cellular, and molecular basis of complex neurological disorders such as Parkinson's and Alzheimer's disease. We employ an interdisciplinary approach, integrating population genetics and genome-scale epigenetic data combined with human pluripotent stem cell (hPSC) and gene editing technologies to study neurological disorders in a genetically controlled and systematic manner in human neuronal cells. We established robust disease-relevant phenotypic readouts using two-dimensional (2D) monolayer and three-dimensional (3D) organoid neuronal culture systems in order to perform unbiased compound and CRISPR/Cas9-based genome-scale screens. Together, this allows us to dissect how genetic, epigenetic, and environmental factors contribute to the development and progression of neurological diseases and to identify novel therapeutic targets. For more details on our lab and research please visit http://www.einstein.yu.edu/faculty/16002/frank-soldner/.
The Albert Einstein College of Medicine, recognized by Forbes as one of the nation's top midsize employers, (http://www.einstein.yu.edu/) provides a highly interactive and stimulating academic environment for scientists in training. The prospective recruit will join our group which consists of postdoctoral fellows, graduate students and technologists. Lab members will participate in programs within the Departments of Neuroscience, Genetics, the Institute for Stem Cell and Regenerative Medicine and throughout the school to further their career development. These include weekly journal clubs, work-in-progress seminars, invited talks, workshops as well as social and professional events organized by the Einstein Postdoc office. We are located in a pleasant residential area in the northeast corner of New York City with an easy commute to Manhattan and the suburbs of Westchester County. We offer competitive salary and benefit packages with optional postdoctoral housing on campus.
Albert Einstein College of Medicine (http://www.einstein.yu.edu/) is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.
We are looking for self-motivated, enthusiastic, and collaborative team members. The ideal candidate should have:
Ph.D. and/or M.D. or equivalent degree in neuroscience, genetics, stem cell biology or any related field
Outstanding record of primary author publications from prior training
Excellent communication and interpersonal skills
Prior experience in any of the following relevant areas is highly desired: stem cell biology in particular human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs), neuronal in vitro culture, molecular and cell biology, molecular genetics and biochemistry. Additional experience in bioinformatics would be preferred.