The Lee Lab at the Medical College of Wisconsin is seeking a highly motivated postdoctoral fellow to participate in a NIH-supported research project investigating the molecular mechanisms of synapse elimination and loss in mature central neurons. The successful candidate will have excellent oral and written communication skills and the ability to work productively both independently and as part of a team composed of students, staff, and collaborating faculty.
Research in the Lee lab is currently aimed at understanding:
1. The role of novel chemokine-like proteins in the regulation of GABAergic synapse (PNAS. PMCID: PMC5798319)
2. The molecular mechanisms of novel synaptic plasticity mediated by exosome-carried signaling molecules (Nat. Commun. PMCID: PMC6109165)
Main techniques used in the lab include electrophysiology, AAV/CRISPR-Cas9 knockout, biochemistry, behavioral tests, immunohistochemistry, and super-resolution imaging.
A background in neuroscience or similar field (PhD or equivalent) with experience in patch-clamping is preferred, but strong candidates who are willing to take electrophysiological training will be also considered. Skills with rodent behavioral tests, surgery, optogenetics, and/or primary neuron culture are plus. Experience in molecular and cellular neurobiology is advantageous.
Interested candidates should send a 1-page statement of research interest, CV, and contact information of three references to Dr. Sang Lee: email@example.com
Internal Number: 25080
About Medical College of Wisconsin
The MCW is the largest private research institution in Wisconsin and ranked among top 50 medical schools in research in America (https://www.mcw.edu/about-mcw). Milwaukee is a metropolitan, yet affordable, city in Wisconsin and provides rich and diverse cultural experience and family-friendly environment.