The Wilcox laboratory is seeking a highly motivated and energetic postdoctoral fellow to work at the interface between basic epilepsy research and therapy development in the department of Pharmacology & Toxicology. Salary and benefits will be commensurate with qualifications and will follow NIH guidelines. The proposed research will capitalize on the use of the first CNS infection-induced mouse model of temporal lobe epilepsy (TLE) to perform state of the art in vivo and in vitro 2-photon imaging experiments using our innovative genetically encoded calcium indicating protein toolkit. In addition, transgenic mice will be employed to study TLE in interacting networks of neurons and microglial cells during the process of epileptogenesis to test the hypothesis that tumor necrosis alpha signaling from microglia to neurons contributes to seizure generation following CNS infection.
University of Utah Job ID# PRN19816B- 00276 - Pharmacology and Toxicology
COMPENSATION: The salary is competitive and commensurate with experience.
WORK SCHEDULE: Full time.
The postdoctoral fellow will participate in a project implementing in vivo and in vitro 2 photon calcium imaging of microglia in a mouse model of infection-induced temporal lobe epilepsy for a newly funded NIH grant. Design, execute, and analyze imaging experiments related to the project. Numerous opportunities for in vitro electrophysiology experiments related to projects exist. Prepare and write manuscripts based on experimental data and present work at meetings.
Minimum qualifications are a Ph.D. or M.D./Ph.D. in neuroscience, bioengineering, pharmacology, or a closely related field. Experience with 2 photon microscopy, video EEG, MATLAB, neuroimmunology, and/or animal models of neurological diseases is preferred. Applicant must have excellent communication skills and work well in a team setting.
Internal Number: PRN19816B
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