We seek a Postdoctoral Research Fellow specializing in imaging animal models of neurodegenerative disorders within Optics @ Martinos, a consortium of research labs at the Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital (MGH) and Harvard Medical School. We have developed an assortment of novel optical microscopy tools to explore multiple facets of brain function and its pathological alterations. Working with Dr. Abbas Yaseen, the fellow will investigate how changes in cerebral energy metabolism, neurovascular signaling, and neuroimmune interactions contribute to neurodegeneration during progression of Alzheimer’s disease (AD). The postdoctoral fellow will use methods based on 2-photon microscopy to explore these pathophysiological hallmarks in vivo in preclinical rodent models of AD. The fellow will also investigate whether prospective preventative and therapeutic methods can counteract disease-related changes in cerebral metabolism and neuroimmunity.
The position is available immediately.
Prospective candidates must be highly motivated with strong experimental and technical skills. A Ph.D. in neuroscience, biomedical engineering, or related field, is required. Experience with optical imaging and handling animals (mice and/or rats) is strongly preferred.
Candidates should be enthusiastic about working in a fast-paced, interdisciplinary environment. The successful candidate will be able to work both independently and collaboratively. Willingness to work with animal models, proficiency with programming (primarily MATLAB or C/C++), and strong written and oral English communication skills are required.
Interested applicants should send a cover letter, up-to-date curriculum vitae, and contact information for three references, to Abbas Yaseen, Ph.D., preferably by email: mayaseen AT nmr.mgh.harvard.edu.
The Martinos Center is home to state-of-the-art imaging facilities and technological expertise in neuroimaging. The center houses over 200 faculty and postdoc members, conducting diverse neuroimaging research with great potential for collaborations and career development.
This position is full-time with benefits and is available immediately. This is initially a one year appointment, with a possibility of extension based on performance review. The Massachusetts General Hospital and Harvard Medical School are equal opportunity and affirmative action employers.
For more information about Optics @ Martinos, please visit www.optics.martinos.org
Candidates must hold a Ph.D. in neuroscience, biomedical engineering, or related field. Detailed knowledge of neurodegeneration and experience with in vivo imaging techniques (including multiphoton or confocal microscopy) is a considerable asset, as is experience with animal experiments. Strong analytical skills, independent motivation, and ability to work in teams are essential for this project.
Applicants should be enthusiastic about working in a fast-paced, interdisciplinary academic environment. The successful candidate will be able to work both independently and collaboratively. Willingness to work with animal models, experience with image and data analysis (using MATLAB, C/C++, and Fiji), and strong written and oral English communication skills are required.
Additional Salary Information: see https://grants.nih.gov/grants/guide/notice-files/NOT-OD-19-036.html
Internal Number: 1
About Martinos Center, MGH/ Harvard Medical School
The Athinoula A. Martinos Center for Biomedical Imaging at Massachusetts General Hospital is one of the world’s premier research centers devoted to development and application of advanced biomedical imaging technologies. Our mission is to advance imaging in healthcare through technology development, translational research and education.
Located on the MGH Research Campus in Charlestown, the Center is home to roughly 100 faculty researchers and more than 200 affiliated and visiting faculty, postdoctoral research fellows and graduate students, who use advanced imaging technologies both separately and in concert to investigate a broad range of biologically and medically important questions.