A postdoctoral position is available for an appropriate candidate to be mentored by Dr. David K. Simon, M.D. Ph.D., Professor of Neurology at Beth Israel Deaconess Medical Center and Harvard Medical School in Boston, Massachusetts. The project focuses on a novel regulatory pathway linking chaperone mediated autophagy (CMA) and the ubiquitin proteasome system (UPS) in the regulation of a transcriptional coactivator, PGC-1alpha. The lab also is studying the role of PGC-1alpha deficiency in Parkinson’s disease (PD), and so this project may help to identify novel therapeutic strategies for PD. Both in vitro studies and transgenic mouse models will be used along with AAV vectors and pharmacological and molecular experimental approaches.
Must have a Ph.D. and/or M.D. or equivalent degrees. Experience in neuroanatomy, histology, molecular biology, tissue culture and mouse models is required. Only candidates with relevant experience should apply. Please send an email briefly describing your research experience and interests. Include a CV and contact information for 2 or 3 references. Send to firstname.lastname@example.org
Additional Salary Information: Salary will depend on years of experience, consistent with the NIH recommended postdoctoral fellow salaries. Fringe benefits will be provided in addition to the salary.
Internal Number: 040119
About BETH ISRAEL DEACONESS MEDICAL CENTER & HARVARD MEDICAL SCHOOL
The David K. Simon laboratory focuses on the pathogenesis of Parkinson's disease (PD), including studies of mechanisms of neurodegeneration as well as translational studies of potential neuroprotective strategies.