The computational life sciences (CLS) group of the IT’IS Foundation in Zurich, pursues simulation-based assessment of interactions between physical exposure (e.g., to electromagnetic (EM) fields) and the physiology of living tissues at different spatial and temporal scales. IT’IS co-develops the leading CLS platform Sim4Life and coordinates the in-silico activities of the NIH SPARC Initiative. A major research focus involves interactions between EM exposure and neural activity, with applications ranging from low-frequency exposure safety (e.g. MRI safety) to neuroprosthetics, electroceuticals, and other therapeutic applications (e.g. DBS,TMS, TACS and Temporal Interference) in the overall context of bioelectronic medicine. For that purpose, electrophysiologically neuro-functionalized, detailed anatomical models are developed and employed, with the goal to gain mechanistic understanding, optimize and personalize devices and treatments, and discover novel therapeutic approaches. Research is performed in international collaborations with world-leading experimental groups (EPFL,MIT, ETHZ, etc.), major device manufacturers, and regulators (e.g FDA).
The CLS group is seeking a creative, talented, and ambitious candidate with an interest in the development of related simulation technology, as well as theoretical and applied modelling studies. Additional topics of interest include uncertainty assessment, validation, optimization, image-based modelling, etc.
The candidate will be an official PhD student aiming at a PhD in Electrical Engineering of the Swiss Federal Institute of Technology (ETH) Zurich, under the supervision of Dr. Cassara' of the IT'IS Foundation and a ETHZ professor of the Department of Information Technology and Electrical Engineering.
The PhD candidate will join a highly motivated and dynamic team working in various rated research areas to conduct independent and original research under supervision on the development of simulation technologies, software tools, and platforms for neurostimulation. As well, the PhD candidate will attend all the curricular activities of regular ETHZ PhD students, including classes, seminars, prepare contributions to international conferences, and teaching activities.
Applicants should have an interest in CLS and a university degree (diploma or master’s) in life sciences, natural sciences (biophysics, physics, mathematics), medical physics, or biomedical engineering.
Preference will be given to applicants with:
- solid programming experience in, e.g., C/C++ and Python (ideally with knowledge of libraries such as NumPy, SciPy, MatplotLib, VTK)
- competences in computational neuroscience (e.g. NEURON (Yale)
- experience with (multi-)physics simulations and numerical analysis
Good organizational skills, high motivation, and flexibility are a plus, as are an excellent ability to work both independently and as part of a team, including external collaborators.
Internal Number: 1
About Foundation for Information Technology in Society (IT'IS)
The Foundation for Research on Information Technologies in Society (IT'IS) is an independent, nonprofit research foundation dedicated to improving and advancing the quality of people’s lives by enhancing the safety and quality of emerging electromagnetic technologies. The Foundation was established in 1999 through the initiative and support of the Swiss Federal Institute of Technology (ETH) Zurich, the global wireless communications industry, and several governmental agencies, and is headquartered in Zurich, Switzerland.
The IT'IS Foundation endeavours to provide an open, innovative and multidisciplinary research environment for the cultivation of sound science and research, and good education and training. Since its inception, it has attained a global reputation in the following research fields:
- Electromagnetic sensor technologies
- Computational electromagnetics in complex environments
- Computational life sciences applied to complex anatomies
- Novel & optimized diagnostics/therapy/treatment planning processes and devices
- Exposure assessments/dosimetry/safety/compliance evaluation
- Electromagnetic exposure systems for biomedical research
Results are widely dis...seminated to the scientific community and the general public through peer-reviewed publications in scientific journals, conference proceedings, white papers, newspaper articles or television interviews.