A postdoctoral fellowship in the Department of Physiology at Yale University in New Haven, CT, USA.
We have been comparing the input and the output of the mouse olfactory bulb to determine the bulb's contribution of olfactory perceptions. In the paper below we showed that the bulb participates in the computation of concentration invariance of odor recognition. Currently we are working to determine the role of the bulb in accommodation. These perceptions are essential for normal animal olfactory behavior.
The experiments involve in vivo optical recordings of membrane potential and calcium in wide-field and 2-photon microscopy.
Storace, D.A. and Cohen, L.B. (2017) Measuring the olfactory bulb input-output transformation reveals a contribution to the perception of odorant concentration invariance. Nature Communications. 8:81. doi: 10.1038/s41467-017-00036-2.
Interest in the scientific problem. Some familiarity with microscopes.
Internal Number: 5713
About Yale University
I have worked on developing optical methods for monitoring brain activity since 1970, first working on voltage sensitive dyes and more recently on genetically encoded voltage indicators (GEVIs). Since 1990 we have simultaneously applied these sensors to the study of neurobiological problems.