Motor Systems Neuroscience and Neural Engineering Laboratory
The laboratory of Dr. Tanuj Gulati at Cedars-Sinai Medical Center, Los Angeles is recruiting a postdoctoral fellow to the study the neural basis of motor skill learning in a NIH funded study. We are a new laboratory (Lab Website: www.gulatilab.org ) that is part of Cedars Sinai’s Center for Neural Science and Medicine. The lab is using systems neuroscience and neural engineering methods to understand the processes of motor skill consolidation in the brain, and also developing novel neurotechnology based on closed-loop electric stimulation, and brain-machine interfaces. Our recent work showed sleep-reactivation of learning-related activity while rats learned a reaching task, and a brain-machine interface task (Gulati et al, Nature Neuroscience 2017; Gulati et al, Nature Neuroscience 2014). Another line of research showed emergence of low-frequency oscillatory (LFO) activity in primary motor cortex (M1) with motor skill consolidation, that also tracked recovery after M1 stroke (Ramanathan*, Guo*, Gulati* et al, Nature Medicine 2018, *equally-contributing authors). This work also showed that boosting the weakened LFO activity after stroke injury using closed-loop electrical stimulation in the rodent model promoted motor performance. This completed work looked at M1 but next aim is to study emergence of learning related activity across distributed motor networks (M1, striatum, cerebellum, motor thalamus) - both during awake and sleep states. Immediate goals are to record jointly from M1 and cerebellum. We plan to do this in intact as well as stroke-injured rodents to identify targets for electrical stimulation. The postdoctoral fellow will use state-of-the-art systems neuroscience approaches to address these questions. Candidate will be expected to perform multi-site recordings in intact rodents, as well as stroke-injured rodent models. They will also be responsible for data analyses, and preparing manuscripts. Candidates will have opportunities to mentor junior trainees (interns/ graduate students). Salary will follow NIH guidelines and is negotiable.
Interested applicants should contact Dr Gulati (email: firstname.lastname@example.org ) with their CV, a description of their research interests, as well as contact information for 2-3 references. Candidates who are attending Society for Neuroscience annual meeting at San Diego in November should also reach out to schedule a meeting.
Applicants are expected to have a PhD in Systems Neuroscience/ Bioengineering or a related discipline. Experience in one of more of the following: data analyses and programming (Matlab/ Python)/ animal training/ experimental neurophysiology - is needed. Candidates with strong experience in computational analyses but limited experimental experience will also be considered.
Internal Number: 18001851
About Cedars Sinai Medical Center, Los Angeles
Cedars-Sinai Health System is among the nation’s leading providers of healthcare services, medical education and medical research, with total annual revenues of $3.3 billion, and is one of the largest non-profit academic medical centers in the U.S. In addition to a large research enterprise, comprising more than 1,500 research projects and a robust technology transfer portfolio, as well as highly sought-after training programs, including more than 400 medical residents and fellows, Cedars-Sinai is widely known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai is a teaching hospital for a variety of regional training programs including the Cedars-Sinai MS and PhD programs, and UCLA.