The Zipfel Lab in the Department of Neurosurgery at Washington University in St. Louis has an immediate opening for a highly motivated candidate to join a fast-paced investigative environment. The laboratory of Dr. Gregory J. Zipfel is broadly focused on investigating molecular mechanisms and developing novel therapeutics for cerebrovascular disease. It uses a complementary set of genetic, molecular, physiologic, and imaging techniques, and employs both in vitro and in vivo experimental models of disease. This position will focus on the lab’s NIH-funded research program investigating the role and mechanisms of vascular oxidative stress on Alzheimer’s Disease, Cerebral Amyloid Angiopathy, and other forms of dementia. The primary focus of the work will include, but is not limited to:
Determining the role of vascular oxidative stress on Alzheimer’s Disease and Cerebral Amyloid Angiopathy.
Elucidating the underlying molecular cascade by which amyloid-b produces vascular oxidative stress.
Identifying the key molecular contributors to vascular oxidative stress-induced formation of cerebral amyloid angiopathy.
Developing novel therapeutics to prevent or attenuate the impact of vascular oxidative stress on Alzheimer’s and Cerebral Amyloid Angiopathy pathogenesis.
PRIMARY DUTIES & RESPONSIBILITIES:
Collaborates with PI on the design, conduct and reporting of research projects.
Significantly contributes to research projects including leadership of research teams or management of projects, leading to publications in peer reviewed journals.
Assists with research proposals for submission to external funding bodies.
Manages research project with other institutions and investigators.
Maintains a thorough knowledge of the advances in specialized fields.
Formulates and conducts research on problems of considerable scope and complexity.
Positive engagement in learning and career development of self and others.
Complies with established safety procedures and maintaining required documentation on laboratory and specimen conditions.
Interested candidates with relevant qualifications should email curriculum vitae including a summary of their research, list of publications, and contact information for three recent references to Gregory J. Zipfel, MD, at ZipfelG@wustl.edu.
Candidates should hold PhD and/or MD with experience in neuroscience/cardiovascular research, molecular biology, confocal imaging, animal surgery and cell signaling techniques.
Ability to work independently and in a highly collaborative, multidisciplinary environment and strong communication and interpersonal skills are required.
Ph.D. in Neuroscience, Immunology, Molecular Biology, and/or MD with training and experience in related fields and have a strong track record of publications in peer reviewed journals.
Ability to work independently and in a highly collaborative, multidisciplinary environment.
Strong communication and interpersonal skills are essential.
Exceptional organizational skills.
Extensive prior experience in cell, molecular and vascular biology or related fields.
Analytical reasoning and problem-solving skills.
Demonstrated working knowledge of standard laboratory policies, procedures and equipment.
Ability to communicate in oral and written form with all levels of personnel and technical publications.
Must be able to work well independently and as a member of a research team.
Internal Number: A001
About Washington University School of Medicine
Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.