Postdoctoral positions are available to investigate mechanisms underlying chronic pain and drug addiction in animals and model cell systems. The goal of this work is to discover cellular and molecular mechanisms that could lead to the development of novel therapeutics for these conditions.
Our location and resources provide an optimal environment for scientists. The Messing laboratory is located within the Dell Medical School in the Health Discovery Building at the south end of the UT Austin campus. Lab space is adjacent to 9 other neuroscience research labs, with shared facilities that include a Nikon Imaging Center, flow cytometry/cell sorting core facility and a newly constructed vivarium. All shared core facilities elsewhere at UT Austin are available for use. The lab is part of the Department of Neuroscience (College of Natural Sciences), the Department of Neurology (Dell Medical School), and the Waggoner Center for Alcohol and Addiction Research. It draws graduate students from two interdisciplinary graduate programs: The Institute for Neuroscience and the Institute for Molecular and Cellular Biology. These groups provide a rich environment for pursuing cross-disciplinary neuroscience research using the latest cutting-edge approaches.
Interested candidates should send their application materials (CV, cover letter and contact information for three references) to email@example.com.
Applicants should have received a PhD in Neuroscience or a related field within the past 3 years, and have expertise in cell and molecular biology and in rodent behavior. Experience in electrophysiology would be considered a plus. The applicant must be highly self-motivated and able to work independently as well as in a team. The applicant also must have excellent time-management and organizational skills, and strong verbal and written communication skills.
Internal Number: 2018-11
About The University of Texas at Austin
The Messing Lab investigates molecular and circuit neuroadaptations to drugs of abuse that contribute to addiction and to co-morbid disorders such as anxiety and pain. The overall goal is to identify drug targets and strategies that could lead to new treatments. We use a variety of molecular and genetic approaches including gene targeting, transgenic expression, gene editing, RNA interference, and transcriptome analysis, together with behavioral pharmacology, electrophysiology, and chemo-/opto-genetics to identify molecules and circuits that drive addictive behavior. Major contributions include determining that protein kinase C epsilon, protein kinase C delta, protein kinase M zeta, N-type voltage-dependent calcium channels, and the type 1 equilibrative nucleoside transporter regulate ethanol intoxication and self-administration in mice. Research on protein kinase C epsilon has led to ongoing efforts to develop inhibitors of this enzyme as treatments for pain, anxiety, and alcohol and nicotine addiction.