Vanderbilt University Medical Center Dept. Neurology
October 8, 2018
Full Time - Entry Level
Academic / Research
We are seeking a post-doctoral researcher to work in the epilepsy brain disorder laboratory at Vanderbilt University Medical Center in Nashville, Tennessee to begin on Sep 1, 2019. Dr. Chengwen Zhou is a neuroscientist and the principal investigator using transgenic animals with GABA receptor subunit mutations and expressing ChR2/NpHR, in vitro brain slice recording, in vivo intracranial EEG, and optogenetic techniques to explore how brain network triggers seizure activity by sleep/emotion-related homeostatic plasticity mechanism. Brain networks involved in normal cognitive processes will also be examined. This postdoc position will be focused on recording brain activity in small animals before and after surgery and in vivo optogenetic manipulation of brain activity. A major goal of the lab is to understand how brain epileptic network/circuits in IGE model lead to seizure onset and co-morbidities such as cognition dysfunction/other diseases.
This position requires a Ph.D. in neuroscience, neurophysiology, or a related field. Prior experience in EEG recordings, proficiency in MATLAB, and small animal surgery is preferred but not required. Both pending Ph.D. graduates and individuals who have completed previous post-doc training will be considered. An excellent academic record is critical, including publications, national meeting presentations, and experience in grant application. Applicants must be reliable, honest, hard-working, independent, and possess excellent communication skills. A minimum time commitment of one year is expected, with the potential opportunity for renewal. Salary will be commensurate with University guidelines, and benefits will be provided.
To apply, please email a cover letter detailing your interest in this position (including your past relevant research, work experiences and career goals), your current curriculum vitae, and contact information for 3 references.
PI: Chengwen Zhou, Ph.D., Assistant Professor of Neurology
Vanderbilt University Medical Center Dept Neurology
MRB III, Suite 6128
465 21st Ave. South
Nashville, TN 37240-7915
Internal Number: 1
About Vanderbilt University Medical Center Dept. Neurology
My lab has recently been set up to study seizures and brain network, which are funded by NIH grants. My interests in neuroscience focus upon how neuronal activity within the whole brain circuits interacts (both cortical and subcortical circuits on microscopic, mesoscopic and macroscopic levels) to generate emerging brain functions such as memory consolidation and epilepsy brain disorders. Particularly my interests focus on how aberrant brain disorders such as seizures, and cognitive co-morbidity deficits are developed within the whole-brain circuits/network due to GABA receptor mutations and how they are intermingled with normal sleep-wake. Using electrophysiological recordings, optogenetic methods and transgenic mice with GABA receptor mutations, this lab will explore intrinsic neuron activity properties, activity-dependent synaptic plasticity within cortical and subcortical network to generate epilepsy brain disorders/cognitive co-morbidity.