Postdoctoral Positions: Metabolism-excitability relations in neurological disorders
We are seeking to fill one or more postdoctoral positions in the Department of Neurology and Neurotherapeutics at UT Southwestern Medical Center in Dallas, Texas. The goal is the functional analysis of synapses and circuits influenced by genes that cause metabolic brain disease (e.g. Glut1, Glut3, pyruvate dehydrogenase, pyruvate carboxylase) primarily in transgenic mice and also in patient-derived cells and data. Projects are funded by multiple National Institutes of Health grants and other sources to identify the cellular, synaptic, circuit and neural network mechanisms by which metabolic genes regulate development, function and plasticity of cerebral cortical, thalamic and cerebellar circuits.
Techniques will primarily employ electrophysiology: whole cell patching and extracellular recordings of synaptic and circuit activity in brain slices and in vivo recording following state-of-the-art genetic manipulation techniques.
Researchers will work in the highly collaborative research environment of the laboratory of Juan M. Pascual, MD, PhD (https://profiles.utsouthwestern.edu/profile/85158/juan-pascual.html), where we incorporate state of the art molecular and biochemical methods with sophisticated functional analysis of circuits to understand the cellular mechanisms by which genes affect brain function and utilize this knowledge to identify therapeutic targets and develop and conduct clinical trials.
UT Southwestern is a premier research facility with state of the art core facilities and extensive career development opportunities for postdoctoral fellows.
To apply, please send a CV, brief description of research interests and three reference letters to Dr. Juan M. Pascual (Juan.Pascual@utsouthwestern.edu) in a message titled ‘Postdoc electrophysiologist position’.
UTSouthwestern Medical Center is an Affirmative Action/Equal Opportunity Employer. Women, minorities, veterans and individuals with disabilities are encouraged to apply.
A PhD or postdoctoral training in neuroscience or related field is required. Experience in electrophysiology is also necessary.
Internal Number: 92194
About UT Southwestern Medical Center
UT Southwestern, one of the premier academic medical centers in the nation, integrates pioneering biomedical research with exceptional clinical care and education. The institution’s faculty includes many distinguished members, including six who have been awarded Nobel Prizes since 1985. The faculty of almost 2,800 is responsible for groundbreaking medical advances and is committed to translating science-driven research quickly to new clinical treatments. UT Southwestern physicians provide medical care in about 70 specialties to more than 105,000 hospitalized patients and oversee approximately 2.4 million outpatient visits a year.
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Research that solves for unmet needs by finding better treatments, cures, and prevention with a commitment to ensuring real world application
Best care possible today, with continuous improvement and innovation for better care tomorrow
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