The postdoctoral position is available immediately and is for a motivated scientist who meets the qualifications and description outlined below. The fellow will investigate the contribution of a transcription factor to the pathophysiology of Parkinson’s disease.
Specifically, we are interested in candidates with a background in neuroscience and Parkinson’s disease.
The overall goal of the project is to study the alpha-synuclein pathology in the context of a Parkinson’s disease-linked mutation. The candidate will use established model systems to determine the effects of this mutation. The results from these studies could lead to the development of novel therapeutic strategies to improve clinical outcomes of Parkinson’s disease. While working with Dr. Brundin and his research team, the candidate will help guide research directions and provide expertise to facilitate the highest level of contribution to reach the project objectives.
The Patrik Brundin lab focuses on pathogenetic mechanisms and pharmacological treatment in cell and animal models of Parkinson's disease. They also study cell replacement therapy with stem cells in attempts to repair brains in animal models of parkinsonism. The group's mission is to understand neurodegenerative diseases and develop new therapies that are of benefit to patients and their caregivers.
Recently, the lab has been involved in one of the most promising developments for a cure, or at least progress in fighting Parkinson’s disease. A new investigational drug originally developed for type 2 diabetes is being readied for human clinical trials in search of the world's first treatment to impede the progression of Parkinson's disease following the publication of the lab’s new research.
Van Andel Research Institute (VARI) provides postdoctoral training opportunities to scientists beginning their research careers. The fellowships are to help promising scientists advance their knowledge and research experience and at the same time support the research endeavors of VARI under the mentorship of a VARI Faculty member.
While this project is currently funded, an integral part of postdoctoral training is the process of preparing a research proposal and writing a fellowship application. All VARI Postdoctoral Fellows are encouraged to apply for external funding as soon as it is practical and reasonable after hire. Receiving a fellowship award provides recognition for both the fellow and VARI!
A Ph.D. or M.D./Ph.D. in neuroscience, biochemistry, and/or molecular and cell biology with expertise in Parkinson’s disease.
Experience with mouse models of neurological disease and knowledge of brain morphology are expected.
Previous experience with molecular and cell biology techniques, stereotaxic surgery, and mouse behavioral studies are also expected.
A strong record of high-impact peer-reviewed publications is highly desirable.
Must provide the names of three individuals who can provide recommendations and present a scientific seminar describing his or her previous research.
Description of a Successful Candidate:
A self-motivated and driven individual who is able to exhibit exceptional research productivity and take responsibility for independent management of the project.
A detail-oriented researcher that thinks critically to effectively design experiments and solve complex research problems.
A strong ability to take initiative and work independently, as well as in a team environment.
A collaborative, hands-on researcher who proactively shares knowledge and expertise with lab members.
Excellent written and oral communication skills.
Additional Salary Information: VARI Postdoctoral Fellows are full-time employees of the Institute and are eligible for VAI’s employee benefits. You will be eligible for the following benefits on your first day of employment:
•Medical, Dental, and Vision insurance
•Institute paid Life and AD&D insurance
•Short and Long Term Disability insurance
•Voluntary Term Life and AD&D Insurance
•Flexible Spending Accounts for medical and dependent care
•Ten (10) Vacation Days
•Nine (9) Paid Holidays
•Full-time employees are awarded the equivalent of 5 days of personal time off (PTO) days at the beginning of each calendar year. You will receive a pro-rated number of days based on the month in which you begin employment.
•401k Retirement Savings Plan (Eligibility begins the first day of the month after the date of hire.)
•Parking within the adjacent Michigan Street Development facility, with annual parking fees paid by VAI.
Internal Number: 00012
About Van Andel Research Institute
Van Andel Institute (VAI) is an independent biomedical research and science education organization committed to improving the health and enhancing the lives of current and future generations. Established by Jay and Betty Van Andel in 1996 in Grand Rapids, Michigan, VAI has grown into a premier research and educational institution. Van Andel Research Institute (VARI), VAI’s research division, is dedicated to determining the epigenetic, genetic, molecular and cellular origins of cancer, Parkinson’s and other diseases, and translating those findings into effective therapies. The Institute is home to more than 300 scientists and support staff that work in on-site laboratories and in collaborative partnerships that span the globe. Van Andel Education Institute (VAEI) is dedicated to strengthening science education, and preparing and motivating individuals to pursue science or science-related professions