University of Illinois - College of Veterinary Medicine
September 11, 2018
Full Time - Experienced
Academic / Research
Two postdoctoral positions are available in the Department of Comparative Biosciences at the University of Illinois at Urbana-Champaign, a leading research university, in the laboratory of Uwe Rudolph. The laboratory integrates mouse molecular genetics, chemogenetics, optogenetics, immunohistochemical, biochemical, and behavioral studies to analyze the physiological and pharmacological functions of neurotransmitter receptors, e.g. GABAA receptor subtypes (see E. Engin et al., Trends in Pharmacological Sciences 2018;39:710-732) for cognition, anxiety and depression. Using genetically modified mice with genomic copy number variations, we are currently interested in studying the role of the enzyme glycine decarboxylase (which has been found to be present on an extra chromosome in some patients with schizophrenia and bipolar disorder) for regulating NMDA receptor function and its effect on signal transduction and behavior.
We are further interested in probing the role of specific intrahippocampal projections for anxiety and fear using optogenetics, and in studying the contribution of defined neuronal cell types and receptors to age-related cognitive dysfunction and cognitive dysfunction after surgery/anesthesia and attempting to prevent or reverse this dysfunction using pharmacological strategies.
Qualified candidates highly motivated for a career in science will hold a Ph.D. in Neuroscience, Psychology, Pharmacology or related subjects. Experience in behavioral analysis and/or optogenetics would be an advantage. The starting date is 12/1/2018 or upon agreement.
Internal Number: VetMed2001_CB
About University of Illinois - College of Veterinary Medicine
College of Veterinary Medicine at Urbana-Champaign