Post Doctoral Fellow - Preclinical Schizophrenia Research
June 29, 2018
Fellowship - Entry Level
Academic / Research
The NIH-funded Nakazawa lab is seeking an independent-thinking, highly motivated postdoctoral fellow to study in the Neuroscience Department at Southern Research (SR). The lab is focused on the cellular mechanisms underlying the positive, negative, and cognitive symptoms of schizophrenia. We utilize genetically-engineered mice to investigate hypofunction of N-Methyl-D-aspartate (NMDA)-type glutamate receptor (NMDAR), which interacts with the major excitatory neurotransmitter of the CNS, glutamate. This hypofunction model of schizophrenia, in which NMDARs are developmentally-deleted from cortical and hippocampal GABA neurons, enables study of the role of NMDARs in the pathogenesis of schizophrenia. The Nakazawa lab is particularly interested in (1) perinatal abnormalities leading to cortical GABAergic dysfunction, and (2) the circuitry mechanisms of hyper-excitable auditory cortex. The NIH-funded postdoctoral fellowship position suits candidates highly motivated to perform in vivo physiology or Ca2+ imaging from awake behaving animals and interested in understanding neuronal circuitry function. A developmental neurobiologist with expertise of handling perinatal mouse brain organs are also welcome. Candidates should be capable of and willing to learn new techniques to perform delicate surgical procedures and must demonstrate abilities to think independently and work collaboratively.
Prospective candidates should include with their application a single PDF the following: a statement of interest describing research experience and future goals, curriculum vitae, and contact information for two references will to provide a letter of support.
Serves as a research trainee for the purpose of enhancing and developing research competencies.
Participates in planning, designing and conducting highly technical and complex research projects under the direction of a supervisor. May or may not work independently.
Participates in writing scientific papers and supports preparations of grant applications.
Trains graduate and undergraduate research assistants in the laboratory.
Performs in vivo physiology or Ca2+ imaging from awake behaving animals
Conducts immunocytochemical experiment to study protein distribution/expression
Contributes to grant application & publications derived from project data
Operates and maintains scientific equipment
Maintains external awareness of scientific discipline through familiarity with current scientific literature
Observes appropriate safety and study requirements by reading, understanding and following Standard Operating Procedures (SOP), Good Laboratory Practice (GLP) requirements and study protocols
PhD in neuroscience or relevant scientific discipline
Experience in neuroscience and/or neuropsychiatry-related research
Experience with mouse and rat behavioral testing and related statistical analyses
Strong background in electrophysiology, neuroanatomy, microscopy, and rodent behavioral testing
Proven ability to work in a collaborative team environment
Excellent verbal and written communication skills
Competency in Microsoft Office Suites Products and other relevant software
Knowledge of use of protective equipment and safety protocol related to handling hazardous materials
Ability to observe appropriate safety and study requirements by reading, understanding, and following Standard Operating Procedures (SOP), Good Laboratory Practice (GLP) requirements, and study protocols as applicable
Ability to learn and perform delicate surgical procedures
Developmental neurobiologist with expertise in handling of perinatal mouse brain organs
Commitment to the development of a dynamic career in science
Internal Number: 3258
About Southern Research
WE'RE SOLVING THE WORLD'S HARDEST PROBLEMS.
We’ve created seven drugs that are helping win the war on cancer. More are on the way. When HIV threatened the world’s future, we helped develop a course of treatment that changed the course of history. We’re creating better ways for you to have cleaner air and water. Our technologies help men and women in uniform remain safe overseas. We’re developing methods to build energy efficient cars out of plant fiber that will get 80mpg. We are Southern Research. We’re taking on the world’s hardest problems. And solving them. This has been our mission since 1941.
Founded in 1941, Southern Research (SR) is an independent, 501(c)(3) nonprofit, scientific research organization with more than 400 scientists and engineers working across four divisions: Drug Discovery, Drug Development, Engineering, and Energy & Environment. SR supports the pharmaceutical, biotechnology, defense, aerospace, environmental, and energy industries as we work on behalf of the National Cancer Institute, National Institutes of Health, the U.S. Department of Defense, the U.S. Department of Energy, NASA, major aerospace firms, utility companies, and other private and gove...rnment organizations. We pursue entrepreneurial and collaborative initiatives to develop and maintain a pipeline of intellectual property and innovative technologies that positively impact real-world problems. SR is headquartered in Birmingham with additional laboratories and offices in Wilsonville, Alabama; Frederick, Maryland; Durham, North Carolina; Cartersville, Georgia; and Houston, Texas.