The Lucas Lab in the Department of Molecular Biomedical Sciences at North Carolina State University is seeking a postdoctoral researcher to join the team in Summer or Fall 2018. We conduct preclinical research in mouse models to understand the mechanisms underlying susceptibility to psychiatric illness. The successful candidate will lead a project investigating how early-life experiences alter brain function and shape the ability to cope with stressful or traumatic events later in life. Initially this project will focus on the causal relationship between puberty onset and inhibitory maturation in the basolateral amygdala, the emotional processing center of the brain, as well as how peri-puberty stress may affect this maturational process and lead to susceptibility versus resilience to fear-, anxiety- and depression-related behaviors later in life. This interdisciplinary project will incorporate several cutting-edge techniques, including optogenetics, chemogenetics, and cell-specific transcriptional profiling, with whole-cell slice electrophysiology and behavioral analysis. The successful candidate will have opportunities to collaborate with other labs in our growing interdepartmental and intercollegiate neuroscience community, as well as with other groups in the Research Triangle (Duke University, University of North Carolina at Chapel Hill, National Institute of Environmental Health Sciences, and local industry). In addition to training in experimental methodology, trainees will receive comprehensive professional development in scientific publication and communication, grant writing, and laboratory management. Ultimately, the primary goal of this position is to facilitate transition of the fellow to an independent scientific career. The initial appointment will be for 1 year with the opportunity for reappointment.
Applicants for this position should have a recent doctoral degree in neuroscience or a related field. Expertise (or a strong desire to gain expertise) in whole-cell slice electrophysiology is required.
Internal Number: 00106894
About North Carolina State University
The Department of Molecular Biomedical Sciences (MBS) is one of three departments at the NC State College of Veterinary Medicine (CVM) and consists of 45 faculty who have a diversity of research, clinical, and teaching interests. MBS trains doctors of veterinary medicine and graduate students interested in research-based careers focused on the discovery of new knowledge about animal and human health and disease and using those findings to enhance animal and human health and well-being.
Our faculty are recognized experts in the fields of cell biology and physiology, neuroscience, pharmacology, cancer biology, developmental biology, environmental science and toxicology, genomics, infectious diseases, radiology, and reproductive biology. Our goals are to advance veterinary medical science through innovative basic and applied research, and by mentoring and inspiring students, providing world-class clinical and diagnostic services, and offering the public the latest knowledge through innovative extension and engagement activities.
Our research faculty work in state-of-the-art research facilities including a transgenic mouse facility where graduate students can participate in resea...rch projects related to mouse and animal genomics.
More information about the department can be found at https://cvm.ncsu.edu/research/departments/mbs.
The CVM is located on the Centennial Biomedical Campus at NC State University and includes state-of-the-art research facilities in the CVM Research building (100,000 square feet) which opened in 2005, the Biomedical Partnership Center (40,000 square feet) which opened in 2017, and the Main CVM Administrative building where 7,000 square feet of laboratory space was recently renovated and an additional 7,000 square feet is currently undergoing renovation.
More than 30,000 patients are diagnosed and treated annually by CVM clinicians and the NC State Veterinary Hospital is a major referral center for veterinarians from throughout the Southeast and (related to the advertised positions) includes active Anesthesiology, Radiology and Neurology services. The patient caseload allows for student and house officer instruction and the opportunity for clinical trials and translational research that advance animal health and well-being. The Veterinary Hospital is composed of the 110,000-square-foot, state-of-the-art Randall B. Terry, Jr. Companion Animal Veterinary Medical Center which opened in 2011, the Equine and Farm Animal Veterinary Center and the Veterinary Health and Wellness Center and Satellite and Field Veterinary Services.
North Carolina State University’s CVM is a dynamic community whose members are dedicated to training veterinarians and basic scientists while advancing animal and human health from the molecular cellular level through entire ecosystems.