In order to understand how brains work we need to map brain circuits. The classical discipline of neuroanatomy, where a central task is to understand circuit connectivity in brains, has undergone a renaissance and rapid growth due to our ability to acquire and analyze whole-brain image data volumes. Our laboratory originally proposed (https://doi.org/10.1371/journal.pcbi.1000334) and is carrying out whole-brain connectivity mapping in the mouse and the marmoset at a mesoscopic scale. We employ an integrated research effort including a high throughput experimental pipeline, analysis of the resulting big data volumes using machine learning methods, and dissemination on the web (http://mouse.brainarchitecture.org/).
As part of in the Brain Initiative Cell Census network, which aims to create a cell-type atlas of the mouse brain, we are engaged in management, analysis and dissemination of cell-type specific data sets to manage, analyze and disseminate whole-brain data sets for mouse pertaining to brain-wide distributions of specific cell types, reconstruction of single neurons projecting across the brain, and single-cell/single-nucleus transcriptome data.
We are recruiting for multiple open positions; application deadline: ASAP
We are seeking a Web Developer who will create, manage and maintain a web portal for the dissemination of a large, integrated data set for creating a cell-type atlas of the mouse brain. A successful candidate will be able to work closely with the team to integrate on-site and cloud based data sets to provide a seamless and smooth user experience accessing and analyzing data.
This is a salaried position, with benefits. Compensation will be set DOE. Applicant must be willing to relocate to Cold Spring Harbor Labs in Long Island NY.
The Mitra laboratory at CSHL combines experimental, computational and theoretical approaches to understand how brains work.
Cold Spring Harbor Laboratory (CSHL), founded in 1890, is a preeminent international research institution, achieving breakthroughs in molecular biology and genetics and enhancing scientific knowledge worldwide.
The institution consists of over 600 researchers and technicians, with expertise in cancer, neuroscience, quantitative biology, plant biology, bioinformatics & genomics. CSHL has collaborations with top clinical institutions including Memorial Sloan-Kettering, Dana-Farber, Johns Hopkins, NYU, Weill Cornell, Columbia University, Yale and UCLA. 50% of our research funding is from private and unrestricted sources, allowing a unique degree of scientific freedom and collaboration.