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Postdoctoral fellow, Three-photon imaging in marmoset neocortex

Employer
University of Minnesota
Location
Minneapolis, Minnesota
Salary
Based on experience and following NIH guidelines ($61,000 – $65,000 per year + benefits)
Closing date
Oct 30, 2024
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Job Details

As part of a new collaboration, the Kara and Zimmermann laboratories at the University of Minnesota are seeking a highly motivated Postdoctoral Fellow to join a cutting-edge research project focused on cellular-resolution imaging of population codes in the neocortex of marmosets. The successful candidate will apply advanced optical imaging techniques to explore the neural population codes involved in visual processing and decision-making across different cortical regions. This project leverages ultra-wide field three-photon imaging and genetically encoded calcium indicators to visualize and study up to 1 million neurons simultaneously. The goal is to unravel the relationship between these neural codes, blood flow changes in individual blood vessels, and fMRI voxels.

Key Responsibilities:
•    Utilize in vivo three-photon optical imaging and other advanced techniques to study large-scale neuronal activity.
•    Investigate neural population codes and their relation to cortical blood flow and fMRI data.
•    Analyze complex imaging data using quantitative and computational approaches.
•    Collaborate with a multidisciplinary team of neuroscientists, optical engineers, fMRI researchers, and data scientists.
•    Present research findings at conferences and contribute to high-impact publications.

Qualifications:
•    Ph.D. in Neuroscience or Biomedical Engineering.
•    Strong quantitative and analytical skills.
•    Experience with in vivo optical imaging (two-photon, three-photon) or electrophysiology.
•    Experience with imaging data analysis and software (e.g., MATLAB, Python).
•    Peer-reviewed publications in systems neuroscience.

Application Process:
Interested candidates should submit the following documents to pkara@umn.edu or janz@umn.edu by November 15, 2024:
1.    Curriculum vitae with a full list of publications.
2.    A cover letter outlining your research experience and suitability for the position.
3.    Names and email addresses of three academic references.


An in-person interview can be arranged at the upcoming SFN meeting in Chicago.


For more information about the labs and ongoing research, please visit the Kara Lab (karalab.org) and Zimmermann Lab (https://www.zimmermannlab.com) websites.

Company

The University of Minnesota faculty, alumni, and researchers have won 29 Nobel Prizes in a variety of fields including physiology or medicine, physics and chemistry. The University of Minnesota is one of America's Public Ivy universities, which refers to top public universities in the United States capable of providing a collegiate experience comparable with the Ivy League. The Twin Cities campus has the sixth largest student body in the United States, with 54,890 students in 2023-24. The Kara and Zimmerman labs are part of the Medical Discovery Team (MDT) in Optical Imaging and Brain Science and the Center for Magnetic Resonance Research (CMRR). This MDT is a multi-disciplinary effort focused on mapping the detailed neural circuits that underlie sensation, perception and complex behaviors. State-of-the-art optical imaging and optical stimulation techniques that provide sub-micron spatial resolution are used in experimental model systems of health, injury and disease. Collectively, the approaches and instrumentation developed in CMRR constitute some of the most important tools used today to study system level organ function and physiology for basic and translational research and are increasingly applied worldwide. The CMRR is currently at the forefront of the Human Connectome project and has among the highest field strength magnets in the world.

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