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Principal Investigator (NIH)

National Eye Institute, National Institutes of Health
Bethesda, Maryland
Salary is commensurate with experience and accomplishments. A full package of benefits is available.
Closing date
Aug 6, 2024

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Job Function
Group Leader (Research)
Position Type
Full Time
Senior Level

The National Eye Institute (NEI), National Institutes of Health (NIH) in the Department of Health and Human Services (DHHS), is seeking applications from talented and highly motivated individuals for Tenure-Track and Tenure-Eligible Investigator positions in its intramural research program. The selected candidates will establish and lead independent and collaborative research programs that employ state-of-the-art approaches to make transformative fundamental and/or translational discoveries. We are especially interested in applicants in ocular developmental and/or neurobiology, human genetics/genomics, aging-associated neurodegeneration and/or therapies (cell, gene and small molecule), and those using innovative single cell, single molecule and/or ‘omics’ technologies.

The broad goals of the NEI are to answer both basic and translational questions in vision research. Specific goals include:

  1. Elucidation of genetic, epigenetic, molecular, and post-translational control mechanisms that guide ocular and/or neural retinal development, aging, and evolution.
  2. Discovery of therapies for ocular/retinal diseases by identifying genetic defects and cellular pathways that contribute to disease pathology.

NEI intramural scientists have access to a full range of resources to support cutting-edge research using advanced animal models, cell/tissue-based approaches (including patient-sourced induced pluripotent stem cells and stem-cell based organoids), human biospecimens, and advanced computational methods. The NIH Clinical Center provides unrivaled opportunities for clinically focused research in collaboration with the NEI Eye Clinic as well as with clinician-scientists at other institutes.

Applicants need not have prior experience in vision research and those with complementary expertise and experience are specifically encouraged to apply. Candidates must have a PhD, MD, or equivalent degree(s) and an outstanding record of published research accomplishments. This position is equally open to basic, translational, and clinical scientists. The positions are not restricted to U.S. citizens. All employees of the Federal Government are subject to federal Standards of Ethical Conduct, and all NIH researchers are expected to abide by the Guidelines and Policies for the Conduct of Research in the Intramural Research Program at NIH (

Salary is commensurate with experience and accomplishments. A full civil-service package of benefits is available. Individuals from groups underrepresented in biomedical research are especially encouraged to apply. U.S. citizenship is not required, and resident or nonresident aliens eligible to obtain a valid employment-authorizing visa are encouraged to apply.

Applicants must submit the following items (please note the first three items must be submitted in PDF format):

  1. Curriculum vitae (CV) including a list of publications
  2. Research Goals document outlining proposed research plans (3 pages max)
  3. Vision and Impact statement outlining long-term goals (2 pages max)
  4. Description of leadership, mentoring, and outreach activities that demonstrate a commitment to increasing diversity, equity, inclusion, and accessibility in science. (Note: This is an important part of the application that will be rated.) (1 page max)
  5. Names of at least three references that may be contacted.

All materials should be submitted to Mica McNair at with the candidate’s name and position title in the subject line. Applications will be reviewed 60 days after this ad first appears and will be accepted until the positions are filled.


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