NeuroSurgery Post Doc- Vemuganti Lab University of Wisconsin

In the lab of Dr. Raghu Vemuganti, Professor and Vice-Chair for Basic Research, Dept. of Neurological Surgery, Univ. of Wisconsin. The lab is supported by several federally funded (NIH and VA) grants.

Focus: To investigate the role of noncoding RNAs (microRNAs, lncRNAs and circRNAs), epigenetics, and epitranscriptomics in secondary brain damage following stroke and traumatic brain Injury (TBI). Proficiency in rodent stroke/TBI models, behavioral analysis, and molecular and cellular techniques, including histopathology, immunohistochemistry, Western blotting, PCR, RNA-seq, and siRNA work, is desirable. Skills in data analysis, bioinformatics, and writing are helpful. Scientific integrity and understanding of research ethics are of paramount importance to work in this lab.

PhD in neuroscience or biomedical sciences and proficiency in English is required. The incumbent is expected to interact with several scientists, post-docs, and grad students working in the Vemuganti Lab.

If interested, submit a CV, a brief cover letter indicating prior research experience, career goals, and names of 2 referees to vemuganti@neurosurgery.wisc.edu.

The University of Wisconsin (Madison, WI, USA) is one of the Big-10 universities with intense biomedical research. Madison is a top place to live in the US. The University of Wisconsin is an equal-opportunity employer and encourages applications from underrepresented groups and women.

Representative publications from the lab:

Mehta SL, Chokkalla AK, Bathula S, Arruri V, Chelluboina B, Vemuganti R (2023) CDR1as regulates ischemic brain damage by controlling miR-7 availability. Molecular Therapy Nucleic Acids 31:57-67.

Chokkalla AK, Jeong S, Mehta SL, Davis CK, Morris-Blanco KC, Bathula S, Qureshi SS, Vemuganti R (2022) Cerebroprotective role of N6-methyladenosine demethylase FTO (fat mass and obesity-associated protein) after experimental stroke. Stroke 54:245-254.

Morris-Blanco K, Chokkalla AK, Arruri V, Probelsky S, Jeong S, Vemuganti R (2022) Epigenetic mechanisms & potential therapeutic targets in stroke. Journal of Cerebral Blood Flow & Metabolism 42:2000-2016.

Davis CK, Bathula S, Hsu M, Morris-Blanco KC, Chokkalla AK, Jeong S, Choi J, Subramanian S, Park JS, Fabry Z, Vemuganti R (2022) An antioxidant and anti-ER stress combo therapy decreases inflammation, secondary brain damage and promotes neurological recovery following traumatic brain injury in mice. Journal of Neuroscience. 42(35):6810-21.

Mehta SL, Vemuganti R (2020) Role of circular RNAs in brain development and CNS diseases. Progress in Neurobiology 186:101746.

Kim TH, Mehta S, Lopez M, Sullivan R, Kim H, Morris-Blanco K, Kim H, Kim C, Vemuganti R (2018) microRNA miR- 7a-5p ameliorates ischemic brain damage by targeting α-synuclein. Science Signaling 11(560). Pii: eaat4285.