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Bioinformatics position in epigenomics and transcriptomics in neurodegeneration

Desplats Lab UCSD
San Diego, California
Bioinformatics Programmer or postdoc salary according to UCSD scales
Closing date
Dec 4, 2022

Job Details

A bioinformatics programmer/computational biologist position (postdoc or carrer position depending on qualifications, experience and career goals) is available at the Desplats Lab, Department of Neurosciences, UCSD. Our research is dedicated to unravelling gene regulatory pathways altered in neurodegenerative disorders like Alzheimer and Parkinson. Studies involve the analysis of large datasets generated from human samples and animal models, including DNA methylation, ATAC-seq, RNA-seq, ChIP-seq and spatial transcriptomics.


We are looking for a sharp, driven and goal-oriented Data Scientist with high proficiency in scientific programming languages, such as R and Phyton, experience creating R packages, github and web repositories to support our cutting-edge technology applications. The candidate will be responsible for developing analysis pipelines, contributing to experimental design and statistical modeling and mining large datasets to validate and integrate cross-sectional and longitudinal data across multiple projects. Previous background in neuroscience and epigenetic analysis is a big plus.


Come and join our vibrant, highly collaborative and diverse team.


Applicants should have a PhD or master’s degree in Biology, Neuroscience, Computer Science, Bioinformatics or related field and previous experience in a research setting.


For further information please contact


To apply for this position please submit CV, a cover letter stating career interests and experience, at



Research in our lab is aimed at elucidating the dynamic mechanisms of DNA methylation, which might contribute to onset and progression of the most prevalent neurodegenerative diseases of the elderly, Parkinson’s and Alzheimer’s. At the center of our work is a strong interest in translational neuroscience, therefore we combine aspects of cellular physiology and molecular neuroscience, integrating the analysis of human postmortem brain samples, transgenic animals and cellular models to address mechanistic questions, while identifying therapeutic targets and providing novel diagnostic tools.

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