The Translational Neuropsychiatry Through Neuromodulation (TN2) laboratory in the Department of Psychiatry at the University of Pittsburgh is seeking to hire a Post-Doctoral Fellow or Research Instructor in Psychiatry. The goal of the lab is to investigate the neurobiology of substance use disorders.
The main focus of the project we are recruiting for is to understand how drug-associated cues acquire their enhanced salience and contribute to relapse vulnerability. To that end, we use multi-electrode single-unit recordings (up to 64 channels) from midbrain dopamine neurons and downstream regions while the rat responds to cues associated with opioids vs. natural rewards. In addition, the lab takes advantage of multiple research tools including but not limited to slice electrophysiology, fiber photometry, optogenetics, chemogenetics, intravenous drug-self-administration, vapor drug self-administration, transcranial magnetic stimulation (TMS), RNAscope, molecular imaging (confocal, fluorescent, etc.), and immunohistochemistry.
This position is ideal for motivated candidates interested in learning/applying multiple approaches to answer important scientific and clinically relevant research questions related to reward and motivation.
The lab position is housed in the Department of Psychiatry, a unique environment for young researchers to foster collaborations, be productive, and develop an independent research program. The Department of Psychiatry is recognized nationally and internationally as one of the premier research and treatment centers in Psychiatry in the United State, and has been ranked first among all Departments of Psychiatry in the U.S. with regard to research funding from the National Institutes of Health (NIH) for the past several years. The department has a longstanding tradition of providing a stimulating learning environment that allows for effective educational experiences for trainees. This position will also provide the opportunity to spend time in Pittsburgh, one of the most livable and vibrant cities in the country.
Applicants should be willing to commit to at least a three-year appointment. Start date is somewhat flexible but ideally by April 2023.
- Ph.D. in neuroscience, psychology, biology, bioengineering or other neuroscience-related disciplines
- Experience with in vivo single-unit electrophysiology
- Matlab or Python coding experience
- A cover letter outlining research accomplishments and career goals
- Curriculum vitae
- List of three references with contact information (mailing address, phone number and e-mail address)
Application should be sent to:
Khaled Moussawi, MD, PhD