Two positions are available. All work in the laboratory is centered around the complement system and neuroinflammatory mechanisms. Projects encompass both basic and translational research. More specifically, ongoing projects involve investigating acute and chronic neuroimmune responses occurring after different types of traumatic brain injuries, including long-term neurodegenerative sequalae of injury. One project is focused on traumatic brain injury as a risk factor for Alzheimer’s Disease. Studies utilize different mouse models of mild and severe brain injury. Techniques will include development of transgenic mice, advanced microscopy, cellular and molecular immune profile analysis, high dimensional analyses, detailed assessments of motor and cognitive functions, and the development of novel therapeutic approaches. The laboratory has been a leader in the development of novel targeted complement inhibitory strategies.
MUSC is located in the beautiful historic district of Charleston, regularly ranked the best small city destination in the U.S. It is also bounded by the Atlantic Ocean and beautiful beaches to the east, and national forests and wildlife refuges to the north and south. MUSC is the state’s top-ranked medical center. For further information or to apply (CV and names of 3 referees), please contact Dr. Stephen Tomlinson