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Post-Doc / Research Scientist I – Neural Circuit Studies

Employer
SRI International
Location
Menlo Park, California
Salary
Salary ranges for this role will vary and are based on several factors
Closing date
Jun 12, 2022
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Job Details

Overview
The Sleep Neurobiology Laboratory at SRI International, located in the beautiful San Francisco Bay Area adjacent to Silicon Valley, has an opening for a Postdoctoral Fellow or Research Scientist I with a background in cellular neurophysiology or integrative neuroscience and expertise in neural circuit studies.

Responsibilities 
The Fellow will work with a team of Research Scientists and technical staff to investigate the properties of neuronal cell types involved in sleep/wake control, their interconnections, and their roles in the neural circuits underlying arousal state control and in the sleep disorder narcolepsy.  Cortical nNOS/NK1 neurons (Williams et al., 2019, Cerebral Cortex 29:1090-1108), TAAR1 (Black et al., 2017, Biol Psychiatry 82:623-633), hypothalamic hypocretin/orexin and MCH neurons (Izawa et al., 2019, Science 365:1308-13) and the sleep disorder narcolepsy are of particular interest.  Opportunities exist to collaborate with scientists involved in drug discovery.  Responsibilities of the position include:

  • Optogenetic, pharmacogenetic, neuroanatomical approaches for manipulation of neuronal activity
  • In vivo recording of brain activity using electrophysiology, fiber photometry and/or microendoscopy and/or Whole-cell brain slice electrophysiological recordings
  • Design, execute, and analyze experiments to investigate the function of specific cell types
  • Work with others to develop a pipeline for large-scale, systematic characterization of the physiological and connectional properties of different neuronal cell types
  • Work with others to develop paradigms to correlate physiological, morphological and molecular properties within a single neuron
  • Seek and evaluate new cutting-edge technologies in related areas
  • Publish/present findings in peer-reviewed journals/scientific conferences
  • Present progress reports to fellow researchers in the laboratory and larger organization

There is a career path from Postdoctoral Fellow to Research Scientist at SRI. Appointment at either level confers eligibility for Principal Investigator privileges.

Qualifications

  • Postdoctoral Fellow: Ph.D. or M.D. in a life science or related discipline with minimum 0-3 years post-PhD experience
  • Research Scientist:  Ph.D. or M.D. in a life science or related discipline with >3 years post-PhD experience
  • Working experience in neurobiology research
  • Experience in brain slice electrophysiology and synaptic physiology and/or
  • Experience with use of viral vectors, stereotaxic surgery and optogenetics/chemogenetics/fiber photometry/ microendoscopy/neuroanatomy
  • Strong data analysis skills and publication record
  • Ability to meet aggressive timelines and deliverables
  • Strong commitment to collaborative teamwork
  • Excellent problem solving and experiment managing skills

Salary ranges for this role will vary and are based on several factors, including geographic location, market competitiveness and equity amongst internal employees in similar roles. SRI has a competitive benefits package, to view details please go to: https://www.sri.com/resources/benefits/.

Background Check
Candidates who receive a conditional offer of employment will be subject to a background check.

EOE/AA
SRI is an Equal Opportunity Employer, making decisions without regard to race, color, religion, creed, sex, sexual orientation, gender identity, marital status, national origin, age, veteran status, disability, or any other protected class.

DEI Statement
At SRI we value different identities, perspectives and experiences. A diverse, equitable and inclusive working environment strengthens our ability to create world-changing solutions that make people safer, healthier and more productive.

 

Company

SRI International is a nonprofit, independent research and innovation center serving government and industry. We provide basic and applied research, laboratory and advisory services, technology development and licenses, deployable systems, products, and venture opportunities.Our research and innovations have led to new industries and products that impact people’s lives every day—from the computer mouse and interactive computing to medical ultrasound, cancer drugs, and much more.SRI bridges the critical gap between research universities or national laboratories and industry. We move R&D from the laboratory to the marketplace to create high value and real innovation. And the platforms we build today are designed to meet tomorrow’s needs. For example, an artificial intelligence project for DARPA led to the development of Siri for Apple’s iPhone.SRI works on some of the world’s most important problems, collaborating across technical disciplines to spark new ideas and solutions. We believe in open innovation, bringing the best talent to the challenge at hand.
Find Us
Telephone
650-859-2770
Location
333 Ravenswood Ave
Menlo Park
CA
94025
US
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