Postdoctoral Fellow, Nervous system degeneration and regeneration

Postdoctoral Position in Neuroscience

Following recent additional funding, the Thomas Lab at Temple University School of Medicine is seeking talented and motivated postdoctoral researchers to join our team focusing on the control of intracellular signaling in nervous system health and disease. We are particularly interested to understand mechanisms of neurodegeneration and of demyelination. We address questions at multiple levels, from in vitro assays to primary cultures of neurons and oligodendrocytes and in vivo mouse genetic and viral-mediated approaches. More details are available at thomaslab.org and in our recent publications and preprints, including:

Niu et al. (2022). Palmitoylation Couples the kinases DLK and JNK3 to Facilitate Pro-degenerative Axon-to-Soma Signaling. Sci Signal 2022 Mar 29;15(727):eabh2674. doi: 10.1126/scisignal.abh2674.

Sanders SS et al. (2020). The palmitoyl acyltransferase ZDHHC14 controls Kv1-family potassium channel clustering at the axon initial segment. ELife Nov 13;9 :e56058. doi: 10.7554/eLife.56058.

Niu et al., (2020). Coupled Control of Distal Axon Integrity and Somal Responses to Axonal Damage by the Palmitoyl Acyltransferase ZDHHC17. Cell Reports 33:108635.

Hernandez LM, Montersino A, Niu J, Guo S, Thomas GM. JAK1 palmitoylation by ZDHHC3/7 is Essential for Neuropoietic Cytokine Signaling and DRG Neuron Survival. BioRxiv doi: https://doi.org/10.1101/2020.11.16.385971.

Applicants should have a Ph.D. in Neuroscience, Cell Biology, Biochemistry or a related field, or should expect to obtain one in the near future. Those with a background in primary culture or in using vivo viral or genetic approaches are particularly encouraged to apply. A strong record of publication and presentation of primary research is highly recommended. Please send a brief statement of research interests, a current CV and contact information for 3-4 references to Dr. Gareth Thomas (gareth.thomas@temple.edu).

Several Thomas Lab Postdoctoral Fellows have gone on to run successful labs of their own or have obtained positions of responsibility in the pharmaceutical or Biotech industries. Temple University is an EEO/AA employer and strongly encourages applications from women and minorities.  Further information is available at https://medicine.temple.edu/departments-centers/basic-science-departments/department-neural-sciences