Postdoctoral Associate

A postdoctoral position is available in the laboratory of Carson Thoreen in the Department of Cellular and Molecular Physiology at Yale School of Medicine. We are a multi-disciplinary lab that studies the mTOR signaling pathway, a master regulator of growth implicated in epilepsy and cognitive disorders. Our lab previously discovered how mTOR post-transcriptionally regulates ATF4 transcription factor, a master regulator of amino acid metabolism (Park et al. Cell Reports, 2017), and terminal oligopyrimidine (TOP) mRNAs, a conserved mRNA family that encode hundreds of essential proteins (Thoreen et al, Nature, 2012; Philippe et al., PNAS, 2020). A position is currently available for creative and motivated candidates to investigate how mTOR dysfunction drives epilepsy and learning disorders. Some familiarity with transcriptome-scale methodology, RNA biochemistry, and basic bioinformatics is desired. Applicants should email a current CV and cover letter describing research interests to carson.thoreen@yale.edu. Lab website: http://campuspress.yale.edu/thoreenlab.