Postdoctoral Fellow- Scripps Research

NIH funded postdoctoral fellow positions are available to participate in a collaborative project involving the Cline, Maximov and Yates Labs at the Scripps Research Institute in La Jolla, CA. The goal of this project is to identify brain cell-type contributions to age- and AD-related synaptic and neuronal decline.  We will use state-of-the-art proteomic methods together with diverse genetic, imaging, electrophysiology and behavioral strategies to assess structural and functional aspects of brain function.

Key Responsibilities:

The postdoctoral fellow(s) will determine protein dynamics in genetically defined brain cell types in animal models of Alzheimer’s Disease using bio-orthogonal non-canonical amino acid tagging (BONCAT) of newly-synthesized proteins and quantitative mass spectrometry, and conduct studies examining cellular and molecular mechanisms contributing to synaptic and neuronal function and plasticity. The candidate will be actively involved in optimizing experimental design, data analysis, data interpretation and preparing manuscripts and presentations.

Qualifications

Required:

-Ph.D. in Biological Sciences, Neuroscience or related discipline.

-background in neuroscience, biochemistry, and proteomics.

-a record of independent research and preparation of manuscripts

-experience with rodent handling and brain research

Preferred

-background in bioinformatics, imaging, electrophysiology

-experience in mouse breeding and genetics

To apply, please email a CV with training and employment history, a statement of research interests and future goals, along with the name and email of 3 references to Dr. Hollis Cline at cline@scripps.edu or Dr. Anton Maximov at amaximov@scripps.edu.

The Scripps Research Institute is committed to a diverse and inclusive environment and is proud to be an equal opportunity employer.  All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.