Indiana University School of Medicine (IUSM) is seeking applications for an Assistant Research Professor in the Alzheimer’s disease and related dementias (ADRD) biomarker discovery and development laboratory. The successful applicant will be a Ph.D. scientist responsible for management and conduct of laboratory projects under the guidance of Senior Research Professor of Neurology, Dr. Jeffrey Dage. Specifically, the successful applicant will be expected to conduct research pertaining to the identification of potential biomarkers through integration of genetics, proteomics, transcriptomics and targeted immunoaffinity data. In addition, the applicant will participate in the design and generation of novel reagents for the specific and reliable measurement of potential ADRD biomarkers in cells, animal models, and human tissues.
A strong publication record with evidence of independent and collaborative publications is desired in one or more of the following areas: ADRD, quantitative analysis of proteins or other biomolecules, quantitative or qualitative protein mass spectrometry, bioinformatic analysis of RNA sequencing data, antibody generation and engineering.
Interested applicants should submit a research statement that outlines past achievements, a curriculum vitae, with the names and contact information for at least three references.
At IU School of Medicine, collaboration is key to effective research in Alzheimer’s disease and related dementias (ADRD). Through the Stark Neurosciences Research Institute, interdisciplinary research teams share resources and facilities that enable interaction and innovation in the basic, translational and population science programs.
Additionally, IU School of Medicine is home to several large NIH/NIA funded efforts focused on advancing ADRD research and creating an ideal environment for researchers.
- The Model Organism Development & Evaluation for Late-Onset Alzheimer’s Disease (MODEL-AD) center at Indiana University School of Medicine is focused on developing the next generation of in vivo AD models based on human data.
- The Target Enablement to Accelerate Therapy Development for Alzheimer’s Disease (TREAT-AD) center at IUSM is a collaboration with Purdue University and provides added infrastructure for developing high-quality research tools and technologies needed to validate and advance the next generation of drug targets for Alzheimer’s disease.
- The Indiana Alzheimer’s Disease Research Center is a leading research resource in Indiana for Alzheimer’s disease and other related dementias. As one of only 32 NIA-designated Alzheimer’s Disease Research Centers in the United States, the center has a thirty year history of continuous NIA sponsored research on AD spanning a broad range from basic cellular/molecular to clinical studies. Translational biomarkers are a current high priority area.
- The Longitudinal Early-onset Alzheimer’s Disease Study (LEADS) is a nationwide study of a rare and particularly devastating early-onset form of Alzheimer’s that afflicts patients younger than 65 years of age. LEADS seeks to understand why some people develop Alzheimer’s disease so early, look for genetic determinants of the disease and track the disease’s progression.
- The National Centralized Repository for Alzheimer’s Disease and Related Dementias serves as the primary resource for samples for all NIA-funded dementia studies.
As the nation’s largest medical school, IUSM is committed to being an institution that not only reflects the diversity of the learners we teach and the patient populations we serve, but also pursues the values of diversity, equity and inclusion that inform academic excellence. We desire candidates who enhance our representational diversity, as well as those whose work contributes to equitable and inclusive learning and working environments for our students, staff, and faculty. IUSM strives to take an anti-racist stance, regularly evaluating and updating its policies, procedures, and practices to confer equitable opportunities for contribution and advancement for all members of our community. We invite individuals who will join us in our mission to advance racial equity to transform health and wellbeing for all throughout the state of Indiana.
Indianapolis is the capital and most populous city in the State of Indiana. It is growing economically thanks to a strong corporate base anchored by the life sciences. Indiana is home to one of the largest concentrations of health sciences companies in the nation. Indianapolis has a sophisticated blend of charm and culture with a wonderful balance of business and leisure. The growing residential base is supported by rich amenities and quality of life –the city possesses a variety of professional sports, arts venues and outdoor recreation areas. Residents of this dynamic city, and surrounding suburbs, enjoy leading educational systems and top-ranked universities, paired with a diverse population. Indianapolis International Airport is a top-ranked international airport, being named “Best Airport in North America” by Airports Council International for many years. For additional information on life in Indy: https://faculty.medicine.iu.edu/relocation.