Research Associate – Electrophysiology (patch clamp)

Semmelweis University
Budapest (HU)
Salary commensurate with experience
Aug 18, 2021
Sep 17, 2021
Job Function
Position Type
Full Time
Mid Level

Research Associate – Electrophysiology (patch clamp)

We are establishing a new research group at Semmelweis University in Budapest, Hungary, led by Botond Roska. The group will carry out research in close partnering with the Institute of Molecular and Clinical Ophthalmology Basel (IOB). This new group's mission is to unravel the complex workings of the human visual system and use the acquired knowledge to develop treatments for eye diseases.

We seek an exemplary scientist to join our efforts in developing therapies for vision loss. The successful candidate will pursue experimental work in testing optogenetic sensor-based gene therapy vectors to restore photosensitivity in the retina. The candidate will use patch-clamp recordings and calcium imaging in post-mortem human retinas. The candidate will also perform data analysis of the recordings and work closely with other experimentalists and data analysts at IOB.

The ideal candidate will have a background in electrophysiology and calcium imaging and be familiar with a broad array of work in neuroscience, including optogenetics and its applications in teasing apart circuit physiology.

Essential Functions

• Perform patch-clamp recordings and calcium imaging on human retinal explants on a regular basis;

• Analyze recordings;

• Contribute to scientific ideas;

• Participate in eye donations;

• Work with high flexibility and willingness to perform experiments outside normal working hours;

• Maintain clear and accurate communication with supervisor and other team members.

Required Education and Experience

• PhD or equivalent experience in Neuroscience or related discipline;

• Experience with patch-clamp recordings;

• Strong computational/data analysis skills; ideally programming in Python and/or Matlab.

Preferred Experience

• Experience with two-photon calcium imaging;

• Track record of scientific excellence and independent thinking;

• Ability to meet timelines and deliverables in a collaborative environment;

• Excellent written and verbal communication skills in English;

• Excellent organizational skills and attention to detail.


• Occasional travel to partner sites required

• Attendance and participation in national and international conferences required

What we are offering:

The remuneration will be highly competitive and will depend on your education and experience. The appointment will initially be for 1 year. After a satisfactory evaluation of the initial appointment, the contract will be extended for a total duration of 5 years with a possibility for further extension.

Additionally, Semmelweis University offers excellent fringe benefits and various schemes to promote a productive and pleasant work environment.

Application / Contact

Interested candidates should submit their application documents as a single PDF file to in English by 30.09.2021. Please include a personal statement, your Curriculum Vitae and indicate the Research Associate – Electrophysiology (patch clamp) on the subject line