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Postdoctoral Research Associate in vitro Electrophysiology

Employer
University of Pittsburgh
Location
Pittsburgh, Pennsylvania
Salary
NSF scale
Closing date
Oct 9, 2021
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Job Details

A postdoctoral scientist position is currently available in the Translational Neuroscience Program, Department of Psychiatry, University of Pittsburgh School of Medicine. Highly motivated candidates with an interest in neocortical circuit function in the primate brain are encouraged to apply.

The position is primarily funded by the NeuroNex program (https://neuronex.org/) of the National Science Foundation (NSF). Our NeuroNex project is part of a multidisciplinary international network of laboratories in Canada (Western University, London; University of Toronto, Toronto), Germany (Georg-August-Universität Göttingen) and the US (Yale University; New York University and University of Pittsburgh). Our network, The Fabric of the Primate Neocortex and the Origin of Mental Representations.  From transcriptomics to single neurons and neuronal networks. (https://www.nxwm.io/about-us/), is dedicated to studying the molecular, cellular, physiological and neural network bases of working memory in the primate brain.

The postdoctoral position in Pittsburgh is based in the laboratories of Drs. Guillermo Gonzalez Burgos and David A Lewis. Our labs are part of the group of laboratories, in our NeuroNex network, using patch clamp electrophysiology in acute brain slices to investigate the cellular physiology of neurons involved in the mechanisms of working memory. The candidate will join a dynamic and vibrant international group of researchers with frequent interactions and discussions.

Our brain slice physiology project plans to study, in vitro, neurophysiological mechanisms that may contribute to activity patterns mediating working memory in the dorsolateral prefrontal cortex and other areas of the primate neocortex. In addition, we plan on using patch-seq methods (https://www.sciencedirect.com/science/article/pii/S2666166720301337) to obtain gene expression data from the recorded neurons. The postdoctoral scientist would also participate in separate NIMH-funded studies of pyramidal neurons and interneurons in primate and mouse brain.

Candidates will investigate cellular/synaptic physiology in brain slices, therefore previous experience using video-microscopy patch clamp techniques in acute brain slices is absolutely required. Knowledge of MatLab and/or Python programming languages is preferred, but not strictly required. Candidates interested in this position should contact Guillermo Gonzalez Burgos (gburgos@pitt.edu). Please send your curriculum vitae, a letter expressing your interest in our project, a summary of research experience and three references.

Company

Translational Neuroscience Program, Department of Psychiatry, University of Pittsburgh
Find Us
Telephone
4126243894
Location
1851 Jancey St
Pittsburgh
PA
15206
US
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