This position is in the laboratory of Dr. Raghu Vemuganti, Professor and Vice-Chair for Basic Research, Dept. of Neurological Surgery, Univ. of Wisconsin. The lab is supported by several federally funded (NIH and VA) grants.
The primary project is to investigate the role of noncoding RNAs (microRNAs, lncRNAs and circRNAs), epigenetics and epitranscriptomics in post-stroke brain damage. Proficiency in rodent stroke models, motor and cognitive function analysis, molecular and cellular techniques including histopathology, immunohistochemistry, Western blotting, PCR and siRNA work is preferred. Data analysis, statistical analysis and writing skills are expected.
PhD in neuroscience or biomedical sciences and proficiency in English are required. The incumbent is expected to interact with several scientists, post-docs, grad students and undergrad students working in Dr. Vemuganti Lab.
If interested, please submit CV, a brief cover letter indicating prior research experience, career goals and names of 2 referees.
University of Wisconsin (Madison, WI, USA) is one of the Big-10 universities with under 1,000 active biomedical research laboratories. Madison is one of the top places to live in the United States. University of Wisconsin is an equal opportunity employer and encourages applications from underrepresented groups and women.
Representative Publications from the Lab:
Mehta SL, Vemuganti R (2020) Role of circular RNAs in brain development and CNS diseases. Progress in Neurobiology 186:101746.
Morris-Blanco KC, Kim T, Lopez MS, Bertogliat MJ, Chelluboina B, Vemuganti R (2019) Induction of DNA hydroxymethylation protects the brain after stroke. Stroke 50: 2513-2521.
Chokkalla AK, Mehta SL, Kim T, Chelluboina B, Kim J, Vemuganti R (2019) Transient focal ischemia significantly alters the m6A epitranscriptomic tagging of RNAs in the brain Stroke 50: 2912-2921.
Kim TH, Mehta S, Lopez M, Sullivan R, Kim H, Morris-Blanco K, Kim H, Kim C, Vemuganti R (2018) microRNA miR- 7a-5p ameliorates ischemic brain damage by targeting α-synuclein. Science Signaling 11(560). Pii: eaat4285.
Mehta SL, Kim T, Vemuganti R (2015) Long noncoding RNA FosDT promotes ischemic brain injury by interacting with REST-associated chromatin-modifying proteins. Journal of Neuroscience 35:16443-16449.