A postdoctoral fellowship position is available for a highly motivated individual interested in the neural circuit mechanisms of schizophrenia. Our laboratory conducts 2-photon laser-scanning microscopy imaging of neuronal activity in awake mice, with a focus on mouse models of 22q11.2 deletion syndrome and 15q11 duplication syndrome, high-risk factors for developing psychiatric disorders, especially schizophrenia and autism, respectively. Preference will be given to applicants who have received their Ph.D. degrees in neuroscience or engineering within the last 3 years and have experience in computational neuroscience and data mining using machine learning methods.
In vivo imaging in awake mice and rats will be performed on 3 dedicated 2-photon microscopes. The fellow will work with a dedicated team of computer scientists. The laboratory also is equipped to perform single-cell electrophysiology, two-photon imaging, and two-photon glutamate uncaging in brain slices.
The fellow will benefit from both an outstanding work environment in the laboratory and a highly collaborative St. Jude community. The successful candidate will join a diverse team of researchers whose efforts are directed toward understanding behavior at the levels of neural circuits, individual neurons, synapses, and molecules. The laboratory is part of the Department of Developmental Neurobiology, which houses specialized departmental shared resources, including an integrated support structure for rodent behavior testing, 3-dimensional brain organoids, in vivo and ex vivo cellular imaging, bioinformatics, production of genetically engineered animal models, single-cell profiling, and advanced image processing and analysis. In addition, numerous institutional shared resources and core facilities support the laboratory by providing expertise and state-of-the-art technologies.
St. Jude Children’s Research Hospital offers an excellent salary and benefits package and is an equal opportunity employer. Interested applicants should apply for job 44826 and include CVs and the names and addresses of 3 references.
Stanislav Zakharenko, M.D., Ph.D.
Department of Developmental Neurobiology, MS 322
St. Jude Children’s Research Hospital
262 Danny Thomas Place
Memphis, TN 38105