Dr. Marks’ laboratory is studying central nervous system mechanisms of involuntary weight loss and wasting (cachexia) during the development of cancer. The project involves the use of in vitro and murine models to understand the impact of peripheral cancers on autonomic nervous system function in the periphery. This project also has an associated clinical trial that will provide samples and data to confirm the basic hypotheses generated in the preclinical work. This NIH-funded study will define mechanisms of autonomic nervous system plasticity in the setting of chronic stress and inflammation, and will test novel therapeutics to address this debilitating condition.
The ideal candidate will have training in the neurobiology of sickness responses and be familiar with neuroinflammation and its associated behavioral responses and neurotoxicity. Experience with human research is desired but not required. Strong organizational and leadership skills are required to handle complex data sets, oversee junior research and integrate with other laboratories in this multi-collaborator project.
Daily responsibilities include designing and conducting experiments, data acquisition and analysis, record-keeping and attending weekly lab meetings to present research findings.
- MD and/or PhD
- Strong background in neuroscience.
- The ideal candidate will have training in the neurobiology of sickness responses and be familiar with neuroinflammation and its associated behavioral responses and neurotoxicity.
- Experience with human research is desired but not required.
- Strong organizational and leadership skills are required to handle complex data sets.
- Oversee junior research and integrate with other laboratories in this multi-collaborator project.
- Solid training in the neurobiology of sickness responses or neuroinflammation at the PhD level.
- Solid experience with neuroanatomical approaches (histopathology, computer-assisted image analysis using programs such as Image J, Stereoinvestigator, Neurolucida; Matlab) and standard techniques in immunohistochemistry, molecular and cellular neurobiology (including large RNAseq datasets).
- Excellent organizational and communication skills, be enthusiastic about their work, and be highly motivated to succeed in a multi-disciplinary/multi-collaborator setting that provides a wealth of opportunities in one of the major universities for neuroscience research in the U.S.
All are welcome
Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or firstname.lastname@example.org.
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