Scientist I-IV, Neuroscience R & D

Location
Chicago, Illinois
Salary
Commensurate with experience
Posted
Feb 20, 2021
Closes
Mar 22, 2021
Position Type
Full Time

Description:

Exicure, Inc. (Nasdaq: XCUR), a pioneer in gene regulatory drugs utilizing spherical nucleic acid (SNA™) constructs, is seeking an experienced and independently motivated scientist to join its expanding neuroscience department. This dynamic position is suited for an individual who possesses a strong background in preclinical in vitro and in vivo neurobiology and thrives in a fast-paced, team-oriented environment. The successful candidate will be responsible for conceptualizing, executing & analyzing experiments as a member of a cross-disciplinary team focused on developing and advancing central nervous system (CNS) programs.  Title will be commensurate with experience.

Responsibilities:

  • Lead scientist on multiple preclinical CNS programs.
  • Broad integration of feedback from other development functions and ability to translate scientific hypotheses into rigorous and innovative study designs.
  • Identify and/or develop & validate in vitro and in vivo assays and technologies to evaluate efficacy, PK/PD relationships and relevant biomarkers (established and novel) to characterize drug candidates.
  • Design, execute, and interpret experiments centered around RNA therapeutics and nucleic acid technologies.
  • Present data internally and at scientific conferences.
  • Function in a team environment by effectively collaborating within and across departments.

Education / Experience:

  • Minimum 2 years post-Ph.D. in a biotech or pharmaceutical organization.
  • Ph.D. in neuroscience (preferred), cellular biology, genetics, biochemistry, molecular biology or related field.
  • Ability to communicate plans effectively to senior management and external stakeholders to align on program strategy.
  • Curious, comfortable with ambiguity, eager to solve problems, results oriented, and a ‘sense of urgency’ to complete tasks and achieve goals.
  • Substantial experience with CNS dysfunction and/or neurodegeneration.
  • Substantial experience with iPSC and induced neuron biology – generation, maintenance, and differentiation.
  • Strong expertise in mRNA and DNA isolation (cells/tissue) and quantification techniques.
  • Familiarity with various imaging techniques, including IHC and ICC.
  • Knowledge of antisense, siRNA or related therapeutic approaches is strongly preferred.
  • Experienced with a wide variety of biochemical techniques, including Western blot, immunoassays and phase separations.
  • Strong interpersonal skills as well as excellent communication and presentation abilities.

Apply for Scientist I-IV, Neuroscience R & D

Already uploaded your resume? Sign in to apply instantly

Apply

Upload from your computer

Or import from cloud storage

Your Resume must be a .doc, .pdf, .docx, .rtf, and no bigger than 1Mb


4000 characters left

When you apply for a job we will send your application to the named recruiter, who may contact you. By applying for a job listed on NeuroJobs Career Center you agree to our terms and conditions and privacy policy. You should never be required to provide bank account details. If you are, please email us.

Similar jobs

Similar jobs