Post Doc Res Assoc (PRN25297B)
We are looking for a postdoc to study the properties of excitatory synapses in human stem cell-derived neurons and organoids. The main goal is to characterize SHANK3-binding partners in human synapses using biochemical and electrophysiological assays and to identify those that are lost or dysregulated by SHANK3 deficiency in association with autism and intellectual disability. We are particularly interested in receiving applications from ambitious researchers with substantial experience in protein-protein interaction biochemistry or slice patch-clamp electrophysiology. Check the following links and references to learn more about the Shcheglovitov lab in the Department of Neurobiology at the University of Utah, Salt Lake City, Utah and our research.
Shcheglovitov lab: http://shcheglovitov-lab.utah.edu
Neurobiology Department: https://medicine.utah.edu/neurobiology-anatomy/
University of Utah: https://uofuhealth.utah.edu/why-utah.php
Salt Lake City: https://www.visitsaltlake.com
Utah: https://www.skiutah.com and https://utah.com/national-parks
• Wang et. al., 2021: “Modeling autism-associated SHANK3 deficiency using human cortico-striatal organoids generated from single neural rosettes”
BioRxiv doi: https://doi.org/10.1101/2021.01.25.428022
• Chiola, Napan, Wang et al., 2021: “Defective AMPA-mediated synaptic transmission and morphology in human neurons with hemizygous SHANK3 deletion engrafted in mouse prefrontal cortex”
Molecular Psychiatry https://doi.org/10.1038/s41380-021-01023-2
• Shcheglovitov A et al., 2013: “Shank3 and IGF1 Restore Synaptic Deficits in Neurons from 22q13 Deletion Syndrome Patients”, Nature https://www.nature.com/articles/nature12618
If you are interested in this opportunity, please email your CV and a cover letter briefly describing your research interests and goals to Dr. Alex Shcheglovitov (firstname.lastname@example.org).
University of Utah Job ID# PRN25297B - 00219 - Neurobiology & Anatomy Labs
COMPENSATION: $50,000 to $70,000
WORK SCHEDULE: Full Time
TO APPLY, VISIT: https://utah.peopleadmin.com/postings/111610
EQUAL EMPLOYMENT OPPORTUNITY
The University of Utah is an Affirmative Action/Equal Opportunity employer. Upon request, reasonable accommodations in the application process will be provided to individuals with disabilities. Please contact the Office of Equal Opportunity and Affirmative Action, 201 S. Presidents Cr., Rm 135, (801) 581-8365 (V/TDD), for further information or to request an accommodation. The University of Utah is committed to diversity in its workforce. Women and minorities are encouraged to apply.