Postdoctoral fellow

A postdoctoral position is available in NIH-funded research project for a talented and motivated postdoctoral fellow to investigate the metabolic and molecular mechanisms of neuroinflammation. The project(s) will focus on developing and utilizing neuronal cell models derived from human induced pluripotent stem cells (iPSC) and preclinical rodent models. The successful candidate will have a strong background in stem cell biology, glial cell biology, molecular biology and immunology to develop and optimize neuronal cell differentiation protocols for application to several disease models. Specific experience with is highly desirable. Strong background in neurobiology, iPSC maintenance and differentiation towards neuronal cell lineages and experience working with mouse models is required.

Only recent graduates (PhD awarded with last 12 months) need apply.

Responsibilities:

• Optimize and apply procedures for the differentiation of iPSC-derived neuronal cell lineages Establish assays for the quantitative analysis of iPSC-derived neuronal cell lineages.
• Establish design and execute high-throughput and metabolic flux assays.
• Perform routine cell culture work to support ongoing projects including maintenance and directed differentiation of pluripotent stem cells to glial lineages.
• Significant experience in standard laboratory techniques flow cytometry, immunofluorescence, PCR, western blots, tissue culture, etc.
• Maintain accurate and complete records and protocols.
• Communicate in written and oral form with a multidisciplinary team.

Please send your CV, a letter of interest and a list of three references per email to Dr. Jaspreet Singh (jsingh2@hfhs.org)