Postdoctoral fellow - Sex differences in neuronal function
Looking to recruit junior or senior post-doctoral fellows to join a project focused on sex-specific signaling in the hippocampus. Boys are diagnosed with autism spectrum disorder (ASD) and other neurodevelopmental disorders more frequently than girls. However, the mechanisms establishing this sex bias remain unknown. Through our work on the genetics of ASD and intellectual disability, we have identified sex-specific intracellular signaling pathways that could be involved in female protection or male susceptibility. We are currently exploring sex differences in the localization and activity of signaling pathways at the synapse and their effect on synaptic function. Please visit our website www.manzinilab.org for more details on our research.
A PhD in Neuroscience or other biomedical discipline is required. Previous research experience in studying sex-specific mechanisms and sex differences is preferred, but we are also interested in candidates with expertise in biochemistry, cell biology, confocal and 2-photon imaging, and/or mouse genetics, who would want to pursue additional training. We are particularly interested in two different research profiles 1) a cell biologist with expertise in live microscopy, FLIM and FRET and 2) a mouse geneticist with an interest in analyzing sex-specific changes in molecular, physiological, and behavioral parameters. Position can be tailored to the applicant’s career aspirations either as a traditional postdoctoral fellow with the freedom to develop a fully independent project within the lab’s research interests or with the possibility to lead existing projects as research staff after an initial period as fellow.
The Manzini lab recently joined the Child Health Institute of New Jersey, a state-of-the-art research facility embedded in the Bristol-Myers Squibb Children’s Hospital and Robert Wood Johnson Hospital. The open floor plan allows for direct interaction with multiple neuroscience laboratories with expertise in synaptic physiology, neural development, endocrinology, and human cell models such as induced pluripotent stem cells. Additional expertise is available in the larger Neuroscience community at Rutgers which counts more than 200 PIs under the umbrella of the Brain Health Institute. Frequent interactions are encouraged via frequent seminars, journal clubs, symposia, and informal meetings. The lab is a friendly and inclusive environment where we hope everyone can do their best science and develop the skills necessary to advance their career.
The CHINJ is located in downtown New Brunswick near public transportation with easy access to New York City and Philadelphia and neighboring towns by New Jersey Transit.
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