Postdoctoral fellow

We are looking for a talented postdoctoral fellow with strong background in histology and good publication record to join our team. We conduct translational research in multiple sclerosis (MS) with the goal of understanding the mechanisms that underlie MS progression and neurodegeneration.

The candidate will participate in our larger effort to determine the population structures of glia cells in MS lesion tissue and to define their interactome in chronic and remyelinating MS lesions (Park et al. Acta Neuropath Comm. 2019).

Our laboratory uses cutting-edge technologies such as (i) highly multiplexed histological imaging (staining of individual section with 40+ antibodies), (ii) advanced computational tools for spatial analysis, (iii) purification of astrocyte and oligodendrocyte nuclei from MS, Alzheimer and Parkinson’s tissue for transcriptomic and genomic profiling with sNuc-Seq and ATAC-Seq and (iv) generation of human iPSC-derived astrocytes and microglia (Ponath et al. Nat Commun. 2018).

Our laboratory is part of the Department of Neurology, Yale School of Medicine, and is embedded in a highly collaborative, translational neuroimmunology program that includes T cell biology, genetics and computational biology. 

The candidate should have a broad neurobiology background and experience with histology/confocal microscopy. Expertise in glial cell culture, FACS and computational biology (sNuc-Seq) is desirable. Please respond with CV, a short description of relevant expertise, representative publications and the names of three references by email to david.pitt@yale.edu. The successful candidate will join my laboratory for a minimum of 3 years on a NIH funded position starting in January 2021.