Intern, In Vivo 2 Photon Imaging

Expiring today

Cambridge, Massachusetts
Nov 02, 2020
Dec 02, 2020
Job Function
Position Type
Part Time
Entry Level

At Eisai, satisfying unmet medical needs and increasing the benefits healthcare provides to patients, their families, and caregivers is Eisai’s human health care (hhc) mission. We’re a growing pharmaceutical company that is breaking through in neurology and oncology, with a strong emphasis on research and development. Our history includes the development of many innovative medicines, notably the discovery of the world's most widely-used treatment for Alzheimer’s disease. As we continue to expand, we are seeking highly-motivated individuals who want to work in a fast-paced environment and make a difference.  If this is your profile, we want to hear from you.
General Summary:

The Eisai Center for Genetics Guided Dementia Discovery (G2D2) is an industry-unique drug discovery biotech with a diverse group of passionate, dedicated and collaborative scientists committed to helping eradicate Alzheimer’s disease and other dementias. Recognizing the potential for human genetics, data sciences and precision chemistry to disrupt the drug discovery paradigm, Eisai established G2D2 to accelerate the discovery of innovative therapeutics. G2D2 is committed to accelerating drug discovery premised upon robust insights from human biology, and driving multi-disciplinary team-based progress towards addressing real unmet patient needs. 

At G2D2, we focus not only on how such data help identify and validate therapeutic targets, but also to guide novel approaches to drug such targets and match them to the right patient at the right time. Our precision chemistry strategy - in the context of insights from human genetics - is uniquely positioned to deliver tailor-designed small molecule, anti-sense oligo-nucleotide, and other solutions for targeted therapeutics.

Our new cutting-edge 50,000-square-foot facility is strategically located in Cambridge, MA, to accelerate collaborations with leading research institutes in this world-class biotech hub. Our facility has been designed around a novel open-lab concept, enabling chemists, biologists, automation and other scientists to work together in a single common and integrated lab space. Our labs include state-of-the-art capabilities in medicinal and process chemistry, in-vitro and in-vivo biology, microscopy, chemical and structural biology, automation and screening, and several other discovery technologies and platforms. 

You will join a highly interactive and collaborative team spanning a broad range of drug discovery capabilities. We highly value both internal and external collaborations, and you will become involved in flexible research models with a range of external scientific partners to accelerate delivery of innovative medicines. As an Eisai employee you will spend at least 1% of your working time with patients and families to ensure that the innovation you drive is based on an understanding of their real needs.

More information about G2D2 is provided here ( and here (, and about Eisai's Neurology strategy and pipeline are provided here (
An internship opportunity at G2D2 provides talented and motivated graduate students an introduction to careers in the pharmaceutical industry. In addition to conducting cutting edge research with G2D2 scientists, interns at G2D2 will:

•           Participate in educational workshops to learn about all aspects of the drug discovery process
•           Join in a lunch-and-learn program with Eisai staff at all levels to learn about diverse job activities and career paths
•           Experience a broad array of networking and socialization opportunities
•           Learn how Eisai makes an impact in patients’ lives through our human health care (hhc) philosophy and have the opportunity to participate in hhc activities

Primary Responsibilities:
* Design and conduct in vivo acute and chronic imaging studies using 2-photon microscopy to explore the role of neuroinflammation in mouse models of Alzheimer's disease
* Analyze imaging data using Imaris, Matlab, or custom image analysis routines

* Currently pursuing a PhD in neuroscience or related field
* Experience with confocal and/or 2-photon microscopy is required
* Experience working with laboratory animals (mice) is required
* Experience with in vivo imaging is a plus
* Rodent surgery skills are a plus
* Experience with image analysis software (Imaris, Matlab) is preferred

Position Type:
* Full time, 6 month appointment at Eisai G2D2 in Cambridge, MA

Eisai is an equal opportunity employer and as such, is committed in policy and in practice to recruit, hire, train, and promote in all job qualifications without regard to race, color, religion, gender, age, national origin, citizenship status, marital status, sexual orientation, gender identity, disability or veteran status.  Similarly, considering the need for reasonable accommodations, Eisai prohibits discrimination against persons because of disability, including disabled veterans.

Eisai Inc. participates in E-Verify. E-Verify is an Internet based system operated by the Department of Homeland Security in partnership with the Social Security Administration that allows participating employers to electronically verify the employment eligibility of all new hires in the United States. Please click on the following link for more information:

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