RWJMS-Institute for Neurological Therapeutics (RINT) at Rutgers is seeking applications for a Postdoctoral Research Associate in the areas of Neurodegeneration and Molecular Neuroscience with a focus on Parkinson’s (PD) and Alzheimer’s disease (AD). The laboratory of Dr. Yoon-Seong Kim has recently joined RINT and is seeking highly-motivated individuals to work on ongoing research as well as pursue their own ideas in a supportive environment. The lab and collaborating partners combine expertise in molecular mechanisms underlying oxidative stress-related nigrostriatal degeneration in PD using a range of rodent and cell-based PD models. Currently, his research is expanding to investigate the molecular mechanisms governing oxidative stress-mediated α-synuclein changes including epigenetic and translational regulation as well as protein aggregation and mitochondrial function using the latest, cutting edge techniques. He has recently introduced the innovative concept of transcriptional mutagenesis (TM) of the SNCA gene and its contribution to PD pathogenesis. This original idea is widely applicable to other neurodegenerative conditions including Dementia with Lewy Bodies (DLB) and Alzheimer’s disease. His research pipeline is highly interdisciplinary and integrates core areas of neurodegenerative diseases. The successful applicants will have the opportunity to work on ongoing NIH-funded projects and will be mentored towards an independent research career in a supportive environment here at RINT at Rutgers.
RO1 project #1: https://grantome.com/grant/NIH/R01-NS100919-02
RO1 project #2: https://grantome.com/grant/NIH/R01-NS101461-01A1
Ph.D. in Biomedical/Biological Science (with a focus on Neurodegeneration within the past 2 years) with background in Molecular Biology, Cell Biology, Biochemistry, Genetics or a related discipline. The ideal candidate should have a strong molecular biology background with accomplishments demonstrated by first-author publications in peer-reviewed journals.
Preferred Qualifications: Training and/or experience with: Basic molecular biology tools and techniques involving DNA, RNA and protein, gene-editing techniques like CRISPR/Cas9, Cell-culture techniques (primary neurons, iPSC culture and differentiation), animal handling and associated surgical techniques including creation of toxin-induced animal models to study Parkinson`s disease (PD) pathogenesis, stereotaxic injection, AAV/lentiviral work, RNASeq and data analysis, mouse/rat- brain immunohistochemistry experience with recombinant protein and neurodegeneration. Training will be provided to the right person as necessary to fill any skill gaps.
How to apply: Please send the following documents directly to Dr. Kim (firstname.lastname@example.org): cover letter, complete CV/resume; one-page statement of research interests and philosophy; and a list of at least three (3) professional references with email addresses.