Postdoctoral Scholar in Stem Cell Biology and Neural Disease Modeling

Baylor College of Medicine
Houston, Texas
Hiring up to $54,756.00
Dec 11, 2019
Feb 09, 2020
Position Type
Full Time

Human Neuronal Differentiation Core (HNDC) is looking for a highly motivated Postdoctoral Scholar to join a research program investigating the molecular basis of neurodevelopmental and neurodegenerative disorders. HNDC supports studies of multiple research groups including those supported through the Intellectual and Developmental Disabilities Research Center (IDDRC). We are using directed differentiation and direct conversion of human pluripotent stem cells (embryonic and patient-derived induced pluripotent stem cells) for application of a wide range of molecular and genetic modifiers to human neurons and elucidation of underlying regulatory gene networks behind the cell phenotype. 

HNDC is part of the Department of Molecular and Human Genetics, an internationally recognized department at Baylor College of Medicine. The core facility is at the Neurological Research Institute of the Texas Children's Hospital, a multidisciplinary and extremely dynamic research environment with state-of-art infrastructure ( In order to support the ongoing projects, the selected candidate will work directly with students and postdocs to design and conduct electrophysiology (patch-clamp and MEA) and calcium imaging experiments using human 2D and 3D neuronal models and investigating contributions of various cells types in neural disease.
This opportunity is ideal for a candidate who desires to build his/her resume either by increasing personal bibliography output or documenting skills relevant for transitioning to industry.

Minimum Qualifications
  • Education: Ph.D in Basic Science, Health Science, or a related field.
  • Training and independence in performing experiments with at least one of the following methods: whole cell patch-clamping and calcium imaging.
  • A preference will be given to applicants with the following experience:  iPSC-derived neurons or primary neuronal cultures and organotypic slices, immunohistochemistry and confocalmicroscopy, multi-electrode array recordings.
  • A strong interest in and research training relevant to the areas of stem cell biology and neural development.
Job Duties
  • Planning and performing advanced research experiments.
  • Establishing new research protocols and procedure.
  • Writing reports on analysis of acquired data.
  • Summarizing findings and assisting with figures for grant proposals and manuscripts.
  • May be responsible for laboratory management.
  • May supervise research staff.

Essential personal qualities important for this job include sense of responsibility, excellent organizational skills, clear and effective verbal/written communication, interest in working in a dynamic setting with various groups, and unfailing desire to understand the brain.

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