A postdoctoral position is available in the laboratory of Dr. Gareth Thomas at the Lewis Katz School of Medicine at Temple University, Philadelphia. Our laboratory focuses on novel mechanisms that regulate neuronal intracellular signaling pathways and seeks to understand how such regulation is impaired in neuropathological conditions. Following recent additional funding, our team is expanding to follow up exciting findings, which reveal that the protein-lipid modification palmitoylation controls the activity and localization of a select group of signaling proteins with strong links to neurodevelopmental and neurodegenerative disease (e.g. Martin et al., 2019, Sci. Rep.; Holland et al., 2016, PNAS; George et al., 2015, eLife).
We address these questions at multiple levels, ranging from biochemical and cell biological assays to viral-based in vivo methods, including genetically modified mice. We are currently seeking to recruit at least one talented, motivated scientist who has recently obtained their Ph.D. or expects to obtain one in the near future. Prior expertise in biochemical and/or cell biological methods using primary neurons, in vivo models of neurodegeneration and/or viral injection techniques would be advantageous.
The Thomas lab is located in Temple University’s recently constructed Medical Education and Research Building and is part of the Shriners Hospitals Pediatric Research Center (SHPRC). The SHPRC consists of several highly interactive groups with expertise in neurodevelopment, neurodegeneration and regeneration. We have excellent core facilities, including 2-photon and multiple confocal microscopes and are located just minutes from downtown Philadelphia, a vibrant city with numerous arts, entertainment, sports and recreational possibilities.
Please send a cover letter with CV and contact information for 3 references to email@example.com. Additional information is available at www.thomaslab.org and https://medicine.temple.edu/departments-centers/research-centers/shriners-hospitals-pediatric-research-center).
A Ph.D. in neuroscience or a related field is required. The ideal candidate should have expertise in neuronal cell biology and/or biochemistry, or prior experience using mouse models of neurodevelopment or neurodegeneration.