Weill Cornell Medicine

About Weill Cornell Medicine

The Hemmings/Platholi lab in the Department of Anesthesiology at Weill Cornell Medicine is interested in the effects of general anesthetics on neurotransmitter release and on their interactions between specific pre- and post-synaptic proteins involved in the control of synaptic transmission and plasticity. We study these effects at the molecular, cellular, functional, and behavioral levels in isolated nerve terminals, brain slices, cultured cells and neurons, and animal models using molecular probes and optogenetic biosensors. Techniques include fluorescence imaging of exocytosis and Ca2+ dynamics, time-lapse imaging of dendritic spines, in-vivo neural ensemble activity using fiber photometry, and electro-physiological approaches.

1 job with Weill Cornell Medicine